Update on the genotyping distribution, epidemiology and associated risk factors in inflammatory disorder in adult subjects: A cross-sectional study

Journal Article

2020

Mahboob, Tayyaba Sultana a, Sadia Mahmood a, Salma Sultana a, K.A. Al-Ghanim b, Z. Ahmed b, Tehniat Shahid c, Ashfaq Ahmad c, Shahid . 2020

Limited molecular studies have been documented with ACE gene polymorphism in OA and RA in the
major industrial city in the country. The current study aims to investigate the prevalence of the arthritis
risks and perform the ACE gene polymorphism in OA and RA in hospital based population. In this
hospital-based study, we adopted 1000 arthritis subjects; 539 was suffering with OA and 461 RA in
the local hospital. Based on the filled questionnaire and signed consent form, patients were involved in
this study. Genotyping was performed in 1000 arthritis subjects. Our results indicated the risk of BMI
and smoking status in both OA and RA diseases. Most of the participants involved in this study were considered
to opt the non-vegetarian rather than the vegetarian. The arthritis patients were interested in eating
the chicken (65.7%) and then red meat (31.5%). Regular walking (22.4%) was found to be higher in the
arthritis patients than the regular exercise (4.7%). However, males are more active than the females in
both the regular exercise and regular walking. Most of the arthritis patients (37.3%) had the comfortable
sleep duration between 9 and 10 h. The prevalence of arthritis has been increased and patients with high
BMI should be growing the risks of the various arthritis. Simultaneously, weight gain is connected with
both the OA and RA diseases. Physical activity is required to reduce the risks of arthritis. The present
study recommends to avoid the smoking and maintain the normal BMI specifically in the females to avoid
the arthritis disease in Faisalabad city in the Pakistan

• Publication Work Type: Research work