Roles of Interdigitated Electrode Geometry in Non-Faradaic Impedimetric Biosensors
In this work, we investigate the effect of interdigitated electrode fingers width and gap on the performance of biosensors. Two
different configurations of interdigitated electrodes were utilized; one consists of 50 μm wide fingers with a gap of 50 μm, and the
other consists of 100 μm wide fingers with a 100 μm gap. First, the active surface area of both interdigitated electrodes was
investigated. Then, the surface electronic parameters were investigated using faradaic and non-faradaic electrochemical impedance
spectroscopy modes. Both interdigitated electrodes were then functionalized with LDL-antibodies through a standard chemical
functionalization route and were utilized for the detection of LDL-antigen of cholesterol. The biosensor with 50 μm width and gap
demonstrated better sensitivity and limit of detection of 6.08 nF/log(ng/ml) and 40 pg ml−1, respectively. Biosensors with 100 μm
finger width and gap sensitivity and detection limit are 5.16 nF/log(ng/ml) and 300 pg ml−1, respectively. The enhanced sensitivity
and limit of detection for the first biosensor is due to the increased surface area, enhanced electric field, and less diffusion of ions
onto the biosensor surface. The study reported here suggests room for improving the geometry of many interdigitated electrodes for
enhanced non-faradaic biosensing performances.
Human cytomegalovirus can cause severe disabilities in newborns, including deafness, blindness, and developmental issues. Current detection methods are expensive, time-consuming, and require…
In this work, we investigate the effect of interdigitated electrode fingers width and gap on the performance of biosensors. Two
different configurations of interdigitated electrodes were…
Wireless sensor networks (WSNs) have attained a great attraction of researchers in
the recent years. In these networks, many structures are considered that have different
…