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SAUD A ALARIFI

Professor

Cell and Molecular Biology, Zoology Department

كلية العلوم
Building 5 AB 98
publication
Book Chapter
2021

Green synthesis of zinc oxide nanoparticles using Anoectochilus elatus, and their biomedical applications

Zinc and its derivatives requirement increased to enhance human immunity against the different pandemics, including covid-19. Green synthesis is an emerging field of research. Zinc oxide (ZnO) nanoparticles have been prepared from Anoectochilus elatus and characterized using absorption, vibrational and electron microscope analysis. They were carried for antibacterial, inflammatory control tendency, and potential antioxidant activities. The brine shrimp lethal assay tested the biologically derived nanomaterial toxicity and the lethal concentration (LC50) is 599.79 µg/ml. The inhibition against the important disease-causing pathogens was measured against four-gram negative, gram-positive bacteria and two fungus pathogens. The nanomaterial exposed inhibition zone for gram-positive bacteria between 17 mm and 25 mm. The inhibition zone against gram-negative bacteria exists between 19 mm and 24 mm. The anti-inflammatory activity was assessed by inhibition of protein denaturation and protease inhibitory activity using nanomaterial. The antioxidant activity was examined using four assays for the therapeutic activities. The average size range of 60–80 nm nanoparticles has prepared and exposed the good biological activity between 50 µg/ml and 100 µg/ml. The comparative results of anti-inflammatory and antioxidant assay results with standards such as Aspirin and vitamin C exposed that two to three times higher concentrations are required for the fifty percent of inhibitions. The prepared low-cost nanoparticle has exhibited excellent biological activity without any side effects and may enhance immunity.

Publication Work Type
research article
Volume Number
2021
Magazine \ Newspaper
Saudi Journal of Biological Sciences
Pages
1-12
more of publication
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The goal of this research is to create a novel Schiff base of chitosan polymer derivatives 1a-1j. Nanotechnology is a promising field since it avoids the usage of hazardous chemicals while also…

by Ponnusamy Packialakshmi, Perumal Gobinath, Daoud Ali, Saud Alarifi, Balasubramani Ravindran, Akbar Idhayadhulla, and Radhakrishnan Surendrakumar.
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publications

Objective

by Sundaram Thanigaivel, Agaram Sundaram Vickram, Vinayagam Saranya, Huma Ali, Saud Alarifi, Jeevan Kumar Reddy Modigunta, Krishnan Anbarasu, Rajasekhar Lakshmipathy, Karunakaran Rohini.
2022
publications

Zinc and its derivatives requirement increased to enhance human immunity against the different pandemics, including covid-19. Green synthesis is an emerging field of research. Zinc oxide (ZnO)…

by Natesan Vijayakumar, Venkataesan Kumari, Bhuvaneshwari Gandhimathi, Kaliyamoorthi Ayyadurai, Rajendran Jayaprakash, Kasi Gopinath, Marcello Nicoletti, Saud Alarifi, AND Marimuthu Govindarajan.
2021