Graphene, an atomically thin two-dimensional carbonaceous material, has attracted tremendous attention in the scientific community, due to its exceptional electronic, electrical, and mechanical properties. Indeed, with the recent explosion of methods for a large-scale synthesis of graphene, the number of publications related to graphene and other graphene based materials has increased exponentially.
1. Education
• Ph.D.: Organic Chemistry, 2005, Central Institute of Medicinal and Aromatic Plants (CIMAP) a CSIR laboratory, Lucknow (UP), India. Degree awarded by Dr. Ram Manohar Lohia Avadh University, Faizabad (UP), India.
Title of thesis: Chemical investigation of some Indian medicinal and aromatic plants and transformation of natural products into bioactive compounds.
• M.Tech.: Post Harvest Engg. & Technology (Food Engg.), 1999, Aligarh Muslim University, Aligarh (UP), India.
Dissertation title: Extraction of natural dyes from agricultural produce including wastes and their application on wool.
• M.Sc.: (Chemistry): Specialization in analytical Chemistry, 1997, Aligarh Muslim University, Aligarh (UP), India.
• B.Sc. (Hons.): Chemistry, 1995, Aligarh Muslim University, Aligarh (UP), India.
2. Professional appointments
February 2009-Present Assistant Professor, Organic chemistry division, Department of chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
April 2006-Dec. 2008 Post-doctoral fellow in natural products chemistry, Korea Forest Research Institute, Seoul 130-712, Republic of Korea, Advisor: Professor Hak-Ju Lee.
Dec. 2005-March 2006 Post-doctoral fellow in natural products chemistry, South China Botanical Garden, Chinese Academy of Sciences, Leyiju, Guangzhou 510650, China,
Advisor: Professor Xiaoyi Wei.
August 2005-Dec. 2005 Scient ist, R & D division, SAMI Labs Ltd., Corporate office, 19/1 & 19/2, I Main, II Phase, Peenya industrial area, Bangalore 560058, India.
April 2000-July 2005 Project Assistant, Phytochemistry division, Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow- 226015, India.
Natural products are organic compounds, which are isolated from natural sources such as plants, microorganisms, marine organisms and animals. These organisms rely mainly on their chemical defense by producing the organic compounds also termed as secondary metabolites. Natural products are a rich source of new pharmaceutical agents. Recent survey indicates that ca.60% of anti-cancer and anti-infective agents that commercially available or in the late stages of clinical trials are of natural products origin. My primary research interest is isolation of new pharmaceutical agents from natural sources, chemical transformations of bioactive natural products, design of activity-guided screening of natural product extracts for medicinal research. Chemotaxonomic studies, chemical fingerprinting of essential oils isolated from various aromatic plants with the help of GC and GC-MS. Various modern chromatographic techniques such as High Performance Liquid Chromatography (HPLC), High Performance Thin Layer Chromatography (HPTLC), Centrifugally Accelerated Radial Thin Layer Chromatography (Chromatotron), Flash Chromatography, Vacuum Liquid Chromatography (VLC), Flash chromatography, Column Chromatography (CC) and Preparative Thin Layer Chromatography (pTLC) are used for the isolation and purification of highly complex polar and non-polar mixtures of bioactive natural products. Structure of the pure secondary metabolites and their modified analogues are established with the help of extensive spectroscopic studies such as one-dimensional (1H-NMR, 13C-NMR and DEPT), two-dimensional (COSY, NOESY, TOCSY, HMQC and HMBC) NMR experiments, HPLC, mass spectrometry (EI, CI, FAB, LC-MS, GC-MS and linked scan), UV and IR spectrophotometers.
areas of expertise
Areas Of Expertise
Natural Products Chemistry, Green nanotechnology, GC-MS, LC-MS, HPLC, Organic synthesis.
A green, one-step approach for the preparation of graphene/Ag nanocomposites (PE-HRG-Ag) via simultaneous reduction of both graphene oxide (GRO) and silver ions using Pulicaria glutinosa plant extract (PE) as reducing agent is reported. The plant extract functionalizes the surfaces of highly reduced graphene oxide (HRG) which helps in conjugating the Ag NPs to HRG. Increasing amounts of Ag precursor enhanced the density of Ag nanoparticles (NPs) on HRG.
The immense importance of nanoparticles and their applications is a strong motivation for exploring new synthetic techniques. However, due to strict regulations that manage the potential environmental impacts greener alternatives for conventional synthesis are the focus of intense research. In the scope of this perspective, a concise discussion about the use of green reducing and stabilizing agents toward the preparation of metal nanoparticles is presented.
Silver nanoparticles have a high antimicrobial activity and are broadly utilized for several disinfection purposes including water and materials’ sanitization for medical purposes. There have been comparatively few studies on using silver against plant pathogenic fungi. In this study, silver nanoparticles (Ag NPs) were used at concentrations of 0.0, 0.0002, 0.0005, 0.0007, 0.0009, 0.0014 and 0.0019 mol/L. Six different Rhizoctonia solani anastomosis groups (AGs) infecting cotton plants were treated in vitro with Ag NPs on Czapek Dox agar (CDA) and potato dextrose agar plates.
The apoptotic and genotoxic potential of titanium dioxide nanoparticles (TiO2NPs) were evaluated in hemocyte cells of freshwater snail Lymnea luteola L. Before evaluation of the toxic potential, mean size of the TiO2NPs was determined using a transmission electron microscopy and dynamic light scattering. In this study, L. luteola were exposed to different concentrations of TiO2NPs (28, 56, and 84 lg/ml) over 96 h.
Mixed metal nanoparticles (NPs) have attracted significant attention as catalysts for various organic transformations. In this study, we have demonstrated the preparation of nickel–manganese mixed metal oxide NPs doped with X% nano cerium oxide (X= 1, 3, 5 mol%) by a facile co-precipitation technique using surfactant and surfactant free methodologies. The as-synthesized materials were calcined at different temperatures (300 C, 400 C, and 500 C), and were characterized
Green synthesis of nanomaterials finds the edge over chemical methods due to its environmental compatibility. Herein, we report a facile and eco-friendly method for the synthesis of palladium (Pd) nanoparticles (NPs) using an aqueous solution of Pulicaria glutinosa, a plant widely found in a large region of Saudi Arabia, as a bioreductant.