Phytochemical profiling, antioxidant potential and cytotoxic activity of Sargassum prismaticum extracts: implications for therapeutic applications
Seaweeds are sources of bioactive compounds with medicinal proper ties, which make them attractive candidates for natural therapeutic agents. Marine brown algae are known to possess anti-inflammatory, hepatoprotective, anticancer properties, etc. Present study was carried out to identify the phytochemical constituents, antioxidant and cytotoxic activities of Sargassum prismaticum in two different solvents viz., chloro form and methanol. Chloroform was found to be the superior solvent for phenol and flavonoid extraction. Antioxidant activity was determined using DPPH and ABTS assays; however, the methanolic extract demon strated better antioxidant potential. The highest cell cytotoxicity with an IC50 value of 7.6 ± 0.02 μg/mL was observed in methanolic extract, while the chloroform extract had an IC50 value of 9.6 ± 0.03 μg/mL against U937 cell line. These finding suggest that Sargassum prismaticum pos sesses potent antioxidant and cytotoxic properties, making it a potential candidate for further study as a novel antioxidant drug source
Phthalates are the emerging environmental toxicants derived from phthalic acid and its constituents, which are moderately present in plastics and many personal care products. Phthalate exposure…
Seaweeds are sources of bioactive compounds with medicinal proper ties, which make them attractive candidates for natural therapeutic agents. Marine brown algae are known to possess anti-…