PUBLICATIONS

Journal Article

PUBLICATIONS:

1. Nonclassical Antifolates, Part 2. Synthesis, Biological Evaluation and Molecular Modeling Study of Some New 2,6-Substituted-quinazolin-4-ones.” F.A.M. Al-Omary, L.A. Abou-zeid, M.N. Nagi, E.E. Habib, A.A.-M. Abdel-Aziz, A.S. El-Azab, S.G. Abdel-Hamide, M.A. Al-Omar, A.M. Al-Obaid, H.I. El-Subbagh. Bioorg. & Med. Chem., 2010, 18, 2849–2863.
Which got the award certificate for the top 25 cited Author 2010-2011 from Elsevier.

2. European Patent EP 2 514 753 A1, Oct. 2012.“6,7-Dihydro-[1,3,4]thiadiazolo-[3,2-a][1,3]diazepin derivatives and pharmaceutical compositions containing the same as hypnotic or anesthetic agent and method for their preparation.”Ghada S. Hassan, Hussein I. El-Subbagh, Mohamed A. Al-Omar, Kamal E. H. El-Taher, Khalid A. Al-Rashood, Abdulrahman M. Al-Obaid, Adel S. Al-Azab, Fatmah A. Al-Omary, Alaa A.-M. Abdelaziz, Mohamed M. Hefnawy.
3. European Patent EP 2 514 754 A1, Oct. 2012. “6,7-dihydro-[1,3,4]thiadiazolo-[3,2-a][1,3]diazepin derivative and pharmaceutical composition containing the same as neuromuscular blocker or skeletal muscle relaxant, and method for the preparation.” Adel S. Al-Azab, Hussein I. El-Subbagh, Khalid A. Al-Rashood, Kamal E. H. El-Taher, Mohamed A. Al-Omar, Ghada S. Hassan, Fatmah A. Al-Omary, Alaa A.-M. Abdelaziz, Mohamed A. Hefnawy.
4. Substituted Thiazoles VII. Synthesis and Antitumor Activity of Certain 2-(Substitued amino)-4-Phenyl-Thiazole Analogues. G.S. Hassan, S.M. El-Messery ,F.A.M. Al-Omary, H.I. El-Subbagh. Bioorg. & Med. Chem. lett., 2012.
5. Substituted Thiazoles VI. Synthesis and Antitumor Activity of New 2-Acetamido- and 2 or 3-Propanamido-Thiazole Analogues. Shahenda M. El-Messery, Ghada S. Hassan, Fatmah A. M. Al-Omary, Hussein I. El-Subbagh. Eur. J. Med. Chem., 2012, 54, 615-625.
6. Substituted Thiazoles V. Synthesis and Antitumor Activity of Novel Thiazolo[2,3-b] quinazoline and Pyrido[4,3-d]thiazolo[3,2-a]pyrimidine Analogues. F.A.M. Al-Omary, G.S. Hassan, S.M. El-Messery, H.I. El-Subbagh. Eur. J. Med. Chem., 2012, 47, 65-72.
7. Nonclassical antifolates, Part 3: Synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. F.A.M. Al-Omary, G.S. Hassan, S.M. El-Messery, M.N. Nagi, E-.E. Habib, H.I. El-Subbagh Eur. J. Med. Chem., 2013,63,33-45.
8. Melatonin: comprehensive profile. Profiles Drug Subst Excip Relat Methodology,F.A.M. Al-Omary. 2013,38,159-226.
9. Nonclassical antifolates, part 4. 5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2, 4-triazole-3-thiols as a new class of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study Hassan, G.S., El-Messery, S.M., Al-Omary, F.A.M., (...), El-Menshawi, B.S., El-Subbagh, H.I. European Journal of Medicinal Chemistry, 66 (2013) 135-145.

10 -Nonclassical antifolates, part 5. Benzodiazepine analogs as a new class
of DHFR inhibitors: Synthesis, antitumor testing and molecular
modeling study, Hussein I. El-Subbagh ,Ghada S. Hassan, Shahenda M. El-Messery
Sarah T. Al-Rashood, Fatmah A.M. Al-Omary, Yasmin S. Abulfadl ,Marwa I. Shabayek .European Journal of Medicinal Chemistry 74,2014, 234-245.

11- “5-Propyl-6-(p-tolylsulfanyl)pyrimidine-2,4(1H,3H)-dione.FatmahA.M.Al-Omary,HazemA.Ghabbour,AliA.El-Emam, C.S. ChidanKumar and Hoong-KunFun .ActaCryst.(2014).E70,o179–o180.
12- “4-(2-Methoxyphenyl)piperazin-1-ium-6-chloro-5-isopropyl-2,4- dioxopyrimidin-1-ide. FatmahA.M.Al-Omary,HazemA.Ghabbour,AliA.El-Emam,C.S. ChidanKumarandHoong-KunFun. ActaCryst.(2014).E70,o245–o246.

13- 3-(Adamantan-1-yl)-4-benzyl-1H-1,2,4- triazole-5(4H)-thione. triazole-5(4H)-thione.
Fatmah A. M. Al-Omary, Hazem A. Ghabbour, Ali A. El-Emam, , C. S. Chidan Kumar and Hoong-Kun Fun, Acta Cryst. (2014). E70, o766–o767

14- Structural and spectroscopic analysis of 3-[(4-phenylpiperazin-1- yl)methyl]-5-(thiophen-2-yl)-2,3-dihydro-1,3,4-oxadiazole-2-thione with experimental (FT-IR, Laser-Raman) techniques and ab initio calculations Fatmah A.M. Al-Omary,Mustafa Karakaya, , Yusuf Sert ,Nadia G. Haress, Ali A. El-Emam, Çağrı Çırakf, Journal of Molecular Structure Volume 1076, 5 November 2014, Pages 664–672.

15-Synthesis, biological evaluation and molecular modeling study of 2-(1,3,4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors ,Al-Rashood, S.T., Hassan, G.S., El-Messery, S.M., , Al-Omary, F.A.M., El-Subbagh, H.I. Bioorganic and Medicinal Chemistry Letters, Volume 24 (2014) 4557–4567

16- Spectroscopic investigation (FT-IR, FT-Raman), HOMO–LUMO, NBO analysis and molecular docking study of 2-[(4-chlorobenzyl)sulfanyl]-4-(2-methylpropyl)-6-[3-
trifluoromethyl)-anilino]pyrimidine-5-carbonitrile, a potential chemotherapeutic agent,
Fatmah A.M. Al-Omary, Asha Raj, K. Raju, C. Yohannan Panicker, , Nadia G. Haress, Ali A. El-Emam, Mahmoud B. El-Ashmawy, Abdulaziz A. Al-Saadi, Christian Van Alsenoy, Javeed Ahmad War Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 146(2014)129–141.

17- Spectroscopic investigations, NBO, HOMO–LUMO, NLO analysis and molecular docking
of 5-(adamantan-1-yl)-3-anilinomethyl-2,3-dihydro-1,3,4-oxadiazole-2-thione, a potential bioactive agent, Fatmah A.M. Al-Omary, Y. Sheena Mary, C. Yohannan Panicker, Ali A. El-Emam, Ibrahim A. Al-Swaidan, Abdulaziz A. Al-Saadi, C. Van Alsenoy,Journal of Molecular Structure 1096 (2015) 1–14.

18-Spectroscopic investigation (FT-IR and FT-Raman), vibrational assignments, HOMO–LUMO analysis and molecular docking study of 2-(Adamantan-1-yl)-5-(4-nitrophenyl)-1,3,4-oxadiazole, Nadia G. Haress, Fatmah Al-Omary, Ali A. El-Emam, Y. Sheena Mary, C. Yohannan Panicker, Abdulaziz A. Al-Saadi, Javeed Ahmad War, Christian Van Alsenoy. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 135 (2015) 973–983.

19- Crystal structure of 3-[(4-benzylpiperazin-1-yl)methyl]-5-(thiophen-2-yl)-2,3- dihydro-1,3,4-oxadiazole-2-thione , Fatmah A. M. Al-Omary, Ali A. El-Emam, Hazem A. Ghabbour, C. S. Chidan Kumar, Ching Kheng Quah and Hoong-Kun Fun Acta Crystallographica Section. (2015). E71, 175–176

20- Crystal structure of 6-(phenylsulfanyl)-5-propylpyrimidine-2,4(1H,3H)-dione, C13H14N2O2S (ZKRIST-NCS.2015-0012). Fatmah Al-OmaryHazem A. GhabbourI, Mohamed I. AttiaI, Hoong-Kun FunI, II and Ali A. El-Emam .Z. Kristallogr. NCS 230 (2015) 289-291 / DOI 10.1515/ncrs-2015-0012,289-291.

21- Study on molecular structure, spectroscopic behavior, NBO, and NLO analysis of 3-methylbezothiazole-2-thione, Satish Chand, Fatmah A.M. Al-Omary, Ali A. El-Emam, Vikas K. Shukla, Onkar Prasad, Leena Sinha, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 146 (2015) 129–141.

22- Crystal structure of 3-{[4-(4-fluorophenyl)piperazin-1-yl]methyl}-5-(thio -
phen-2-yl)-2,3-dihydro-1,3,4-oxadiazole-2-thione, C17H17FN4OS2
Fatmah A. M. Al-OmaryI, Haitham AlRabiahI, Hazem A. GhabbourI, Ching Kheng QuahII, Hoong-Kun FunI and Ali A. El-Emam , Z. Kristallogr. NCS 230 (2015) 267-268 / DOI 10.1515/ncrs-2015-0018,267-268.

23- Crystal structure of 6-(phenylsulfanyl)-5- propylpyrimidine-2,4(1H,3H)-dione, C13H14N2O2S, F.A.M. Al-Omary, H.A. Ghabbour, M.I. Attia, H.-K. Fun, A.A. El-Emam, Zeitschrift für Kristallographie - New Crystal Structures (De Gruyter, Germany),2015, Vol. 230, p. 289-291.
24- Crystal structures of 3-{[4-(4-fluorophenyl)piperazin- 1-yl]methyl}-5-(thiophen-2-yl)-2,3-dihydro-1,3,4- oxadiazole-2-thione, C17H17FN4OS2, F.A.M. Al-Omary, H.A. Ghabbour, 0.152 (Q4) C.K. Quah, H.-K. Fun, A.A. El-Emam, Zeitschrift für Kristallographie - New Crystal Structures (De Gruyter, Germany),2015, Vol. 230, p. 267-268.
25-Interaction of Some New 2-(Substituted-thio)-quinazolin-4-one Analogues with Molybdenum Hydroxylases: A Pharmacophore Prediction.” H.I. El-Subbagh, M.A. Al-Omar, A.A.-M. Abdel-Aziz, F.A. Al-Omary.Future Journal of Pharmaceutical Sciences1 (2015) 50-56

26- Crystal structure of 1-(adamantan-1-yl)-3-(4-chlorophenyl)thiourea, C17H21ClN2S
Fatmah A. M. Al-Omary, Hazem A. GhabbourI,II, Haitham AlRabiahI, Ebtehal S. Al-AbdullahI, and Ali A. El-Emam, Zeitschrift für Kristallographie - New Crystal Structures,2016, Vol. 231 , p. 707-709.

27-Crystal structure of 6-(4-chlorophenyl)-3-(thiophen-2- yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, C13H7ClN4S2, F.A.M. Al-Omary, H.A. Ghabbour,H. AlRabiah, L.H. Al-Wahaibi, A.A. El-Emam, Zeitschrift für Kristallographie - New Crystal Structures (De Gruyter, Germany),2016, Vol. 231, p. 931-032 .

28-Crystal structure of 1-(adamantan-1-yl)-3-(4- bromophenyl)thiourea, C17H21BrN2S, F.A.M. Al-Omary, L.S. Al- Rasheed, H.A. Ghabbour, A.A. ElEmam, Zeitschrift für Kristallographie - New Crystal Structures (De Gruyter, Germany),2016, Vol. 231, p. 1033-1035 .

29-Spectroscopic and electronic structure calculation of a potential antibacterial agent incorporating pyridodipyrimidine-dione moiety using first principles, S. Fatma, A. Bishnoi, V. Singh, F.A.M. Al-Omary, A.A. El-Emam, S. Pathak, R. Srivastava, O. Prasad, L. Sinha, Journal of Molecular Structure (Elsevier, UK),2016, Vol. 1110, p. 128-137 .

30-Molecular conformational analysis, reactivity, vibrational spectral analysis and molecular dynamics and docking studies of 6-chloro-5- isopropylpyrimidine-2,4(1H,3H)-dione, a potential precursor to bioactive agent, F.A.M. Al-Omary, Y.S. Mary, S. Beegum, C.Y. Panicker, M.M. AlShehri, A.A. El-Emam, S. Armaković, S.J. Armaković, C. Van Alsenoy, Journal of Molecular Structure (Elsevier, UK),2017, Vol. 1127, p. 427-436.

31-Crystal structure of 1-(adamantan-1-yl)-3-(3- chlorophenyl)thiourea, C17H21ClN2S, F.A.M. Al-Omary, L.S. Al- Rasheed, H.A. Ghabbour, A.A. El-Emam,
Zeitschrift für Kristallographie - New Crystal Structures (De Gruyter, Germany),2017, Vol. 232, p. 33-35.
32- Crystal structure of 3-(adamantan-1-yl)-1-(4- bromophenyl)urea, C17H21BrN2O, F.A.M. Al-Omary, L.S. Al- Rasheed, H.A. Ghabbour, A.A. El-Emam, Zeitschrift für Kristallographie - New Crystal Structures (De Gruyter, Germany),2017, Vol. 232, p. 37-39.
33- Crystal structure of 2-[3,5-bis(trifluoromethyl)- benzylsulfanyl]-5-(5-bromothiophen-2-yl)-1,3,4- oxadiazole C15H7BrF6N2OS2, F.A.M. Al-Omary, F.S. Alanazi, H.A. Ghabbour, A.A. El-Emam, Zeitschrift für Kristallographie - New Crystal Structures (De Gruyter, Germany), 2017, Vol. 232, p. 131-133.

34-Synthesis, vibrational spectroscopic investigations, molecular docking, antibacterial studies and molecular dynamics study of 5-[(4- nitrophenyl)acetamido]-2-(4-tertbutylphenyl)benzoxazole, Y.S. Mary, M.M. Al-Shehri, F.A.M. Al-Omary, K. Jalaja, A.A. ElEmam, C.Y. Panicker, S. Armaković, S.J. Armaković, O. Temiz-Arpaci, C. Van Alsenoy, Journal of Molecular Structure (Elsevier, UK),2017, Vol. 1133, p. 557-573.

35-Bioactivity and chemical characterization of Acalyphafruticosa Forssk. growing in Saudi Arabia, G.A. Fawzy, A.M. Al-Taweel, S. Perveen, S.I. Khan, F.A. Al-Omary
, Saudi Pharmaceutical Journal (Saudi Pharmaceutical Society),2017, Vol. 25, p. 104-109.

36- A combined experimental and theoretical DFT (B3LYP, CAM-B3LYP and M06-2X) study on electronic structure, hydrogen bonding, solvent effects and spectral features of methyl 1H-indol-5- carboxylate, H. AlRabiah, S. Muthu, F.A.M. Al-Omary, A.-M.S. Al-Tamimi, M. Raja, R.R. Muhamed, A.A. El-Emam, Macedonian Journal of Chemistry and Chemical Engineering,2017, Vol. 36 p. 59-80 .

37- Crystal structure of Crystal structure of (Z)-3- (adamantan-1-yl)-1-(3-chlorophenyl)-Sbenzylisothiourea, C24H27ClN2S., A. A. El-Emam, F. A. M. Al- Omary, L. S. Al-Rasheed, H. A. Ghabbour, E. S. Al-Abdullah,2017, Vol. 232, p. 453-456.

38- Insight into the reactive properties of newly synthesized 1,2,4-triazole derivative by combined experimental (FT-IR and FR-Raman) and theoretical (DFT and MD) study, Y. S. Mary, F. A. M. Al-Omary, G. A. E. Mostafa, A. A. El-Emam, P. S. Manjula, B. K. Sarojini, B. Narayana, S. Armaković, S. J., Journal of Molecular Structure (Elsevier, UK),2017, Vol. 1141, p. 541-550.

39- Experimental (FT-IR, Laser-Raman and NMR) and theoretical spectroscopic analysis of 3-[(Nmethylanilino)methyl]-5-(thiophen-2-yl)-1,3,4- oxadiazole-2(3H)-thione, Y. Sert, N. Öztürk, F. A. M. Al- Omary, C. Alaşalvar, M. M. AlShehri, A. A. El-Emam, H. Gökce, Journal of Theoretical and Computational Chemistry (World Scientific, USA),2017, Vol. 16, Article 1750024 (1-20).

40-Gliclazide: comprehensive profile. Profiles Drug Subst Excip Relat Methodology,F.A.M. Al-Omary. 2017,42 ,125-192.

41-Theoretical investigations of two adamantane derivatives: A combined
X-ray, DFT, QTAIM analysis and molecular docking, Lamya H. Al-Wahaibi, Subramaniam Sujay, Gangadharan Ganesh Muthu, Ali A. El-Emam, , Natarajan S. Venkataramanan, Fatmah A.M. Al-Omary, Hazem A. Ghabbour, , Judith Percino f, Subbiah Thamotharan,, Journal of Molecular Structure, 1159 (2018) 233-245
42- 4-(Adamantan-1-yl)-1-arylidene-3-thiosemicarbazides, 4-Arylmethyl
N′-(Adamantan-1-yl)piperidine-1-carbothioimidates, and Related Derivatives"
Aamal A. Al-Mutairi , Monirah A. Al-Alshaikh , Fatmah A. M. Al-Omary , Hanan M. Hassan , Areej M. El-Mahdy and Ali A. El-Emam, Molecules 2019, 24, 4308.

43- X-ray and theoretical investigation of (Z)-3-(adamantan-1-yl)-1-(phenyl or 3-chlorophenyl)-S-(4-bromobenzyl)isothioureas: an exploration involving weak non-covalent interactions, chemotherapeutic activities and QM/MM binding energy", Al-Omary, Fatmah,, Chowdary Gude, Nikhila , Al-Rasheed Lamees , Alkahtani, Hamad, Hassan, Hanan, Al-Abdullah, Ebtehal, El-Emam, Ali, Percino, Judith, Journal of Biomolecular Structure and Dynamics , 2020, 1-16.

44- Adamantane-linked thiourea, isothiourea and related derivatives: Synthesis, in vitro antimicrobial and anti-proliferative activities, Under publication.

45- X-ray and theoretical investigation of (Z)-3-
(adamantan-1-yl)-1-(phenyl or 3-chlorophenyl)-S-
(4-bromobenzyl)isothioureas: an exploration
involving weak non-covalent interactions,
chemotherapeutic activities and QM/MM binding
energy. Fatmah A. M. Al-Omary, Nikhila Chowdary Gude, Lamees S. Al-Rasheed,
Hamad N. Alkahtani, Hanan M. Hassan, Ebtehal S. Al-Abdullah, Ali A. El-
Emam, M. Judith Percino & Subbiah Thamotharan
JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS
2022, VOL. 40, NO. 6, 2530–2545.
link to this article: https://doi.org/10.1080/07391102.2020.1840443

46- Crystal structure of 5-(adamantan-1-yl)-3-[(4-trifluoromethylanilino)methyl]-
2,3-dihydro-1,3,4-oxadiazole-2-thione, C20H22F3N3OS (NCRS-2022-0144) Lamya H. Al-Wahaibi, Hazem A. Ghabbour, Fatmah A. M. Al-Omary, Edward R. T. Tiekink and Ali A. El-Emam. Z. Kristallogr. - N. Cryst. Struct. published online May, 2022.

47- In vivo Anticonvulsant and Neurotoxicity Evaluation and Docking Study of Promising Novel [1,5]-Benzodiazepine Derivatives",
El-Gamal, Kamal; El-Morsy, Ahmed; Sherbini, Farag; Abdel-. Elraheim, Adel; Ayyad, Rezk; Saad, Ahmed; Al-Omary, Fatmah; Mansour, Basem
Delta University Scientific Journal (DUSJ), Volume 5, Issue 2, December 2022, Pages 153-186

48- Novel Adamantane-Linked Isothiourea Derivatives as Potential Chemotherapeutic Agents: Synthesis, Structural Insights, and Antimicrobial/Anti-Proliferative Profiles, ACS Omega,2023, Volume 8, Pages 13465-13477