Skip to main content
User Image

انتصار سليمان السحيباني


عضو هيئة تدريس

مركز الدراسات العلمية والطبية
كلية العلوم مبنى 5. الدور الثالث. مكتب 95
Journal Article

Ginger Oil Effect as Apoptosis Inducer in Colorectal (Caco-2) Cancer Cell Line

Al-Suhaibani, Entissar S. . 2015

Natural compounds have been used to treat cancer because of their low cytotoxicity and less adverse effects. Ginger has long been used in traditional medicine as it contains active phenolic compounds that have antioxidant, anti-cancer, anti-inflammatory, antiangiogenesis and antiartherosclerotic properties. We investigated the inhibitory activity of GO against colon cancer (Caco-2) cells viability or proliferation. Cells were incubated with GO at concentrations, 0.2%, 0.25, 0.3 to 0.35% of the volume of the media for 72 h at 37°C and 5% CO2. GO dose-dependently inhibited the viability and proliferation of colon cancer (Caco-2) cells in vitro. IC50 concentration of GO on treated cells inhibited proliferation and induced apoptosis even by DNA fragmentation besides caspase-3 reaction over expression. Future study will may deal with further investigations of the possible usages of GO as a new alternative chemotherapeutic agent specially for human colon cancer and other types of cancer

Publication Work Type
ورقة بحثية
Volume Number
Issue Number
Magazine \ Newspaper
International Journal of Advanced Research
more of publication

Aphids are important agricultural pests worldwide. Their control is largely based on chemical insecticides. One species that shows important invasive abilities and hostplant- related differences…

by Entissar AlSuhaibani, Costas Ch. Voudouris, Raed Al-Atiyat, Aise Kotzamumin, John Vontas, John T. Margaritopoulos

Previously, a plant steroid, diosgenin, altered cell cycle distribution and induced apoptosis in human osteosarcoma
cell line. The study objective was to investigate if antiproliferative…

by Entissar S. Al-Suhaibani, Nermin El-Morshedi

Capsaicin (8-methyl-N-vanillyl-6-nonenamide), possesses anti-proliferative properties that can be used as anticancer

by Entissar S. Al-Suhaibani, Nermin El-Morshedi