Semibath Polymerization Approach for One Pot Synthesis of Temperature- and Glucose-Responsive Core-Shell Nanogel Particles
Hezam, Aslam Khan*, Ahmed Mohamed El-Toni, Javed Alam, Ali Aldalbahi, Mukhtar Ahmed, Joselito Puzon Labis, Tansir Ahamad, Mahmoud . 2018
Herein, we report a simple and easy procedure for the synthesis of core-shell structures of glucose-sensitive 3-acrylamidophenylboronic acid (APBA) and temperature-responsive P(NIPAm-AAc) shell nanogel particles using MBA as a cross-linker via free radical polymerization. The synthesized particles were approximately 100 nm and were cross-linked to one another. The shell thickness of the nanogel particles was adjusted by increasing the concentrations of NIPAm through the semibath approach during the process of polymerization. The synthesized colloidal nanogel particle shows thermoresponsive behaviors. The dynamic light scattering technique also confirmed the change in the size of particles dispersed in an aqueous solution upon increase/decrease in temperatures, which is the result of its volume phase transition temperatures (VPTT). The size and morphology of the particles were characterized by TEM, FE-SEM, and AFM. The sensitivity of these nanogel particles to temperature and glucose suggests that they have the potential for applications related to the delivery of self-regulated insulin.
Herein, we report a simple and easy procedure for the synthesis of core-shell structures of glucose-sensitive 3-acrylamidophenylboronic acid (APBA) and temperature-responsive P(NIPAm-AAc) shell…
Bifunctional catalysts for water electrolysis are important for renewable and clean energy transformation processes like fuel cells, lithium−oxygen batteries, and so forth. Despite tremendous…
A series of hollow fiber (HF) membranes made from nanocomposites of polyethersulfone (PES) and graphene oxide (GO) at GO concentrations of 0.2%, 0.5%, and 1.0% were prepared by the dry–wet…