Heterocycles in Medicinal Chemistry (PHC 559)

Welcome to the course on Principles and Advanced Topics in Heterocyclic Chemistry. This course delves into the fundamental principles and explores the latest advancements in the synthesis and reactivity of pharmacologically active heterocyclic compounds. A particular focus will be placed on commonly used strategies for synthesizing medicinally important heterocycles, with an emphasis on recent breakthroughs. Additionally, the course will cover the synthesis of intermediates utilized in constructing aromatic heterocycles. Throughout the duration of the course, we will explore a diverse range of fascinating ring systems, including azoles, pyridines, pyrimidines, quinolones, isoquinolines, as well as fused heterocyclic compounds such as indoles, benzimidazoles, and purines. Join us on this captivating journey into the intricacies of heterocyclic chemistry and uncover the key principles and cutting-edge advancements in this field.