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نوال أحمد عبدالرحمن العرفج

Professor

أستاذ دكتور في الكيمياء التحليلية/قسم الكيمياء/كلية العلوم

كلية العلوم
المدينة الجامعية للطالبات - كلية العلوم (مبنى 5) - الدور 3 - مكتب 336
المنشورات
مقال فى مجلة
2022

Ultrasensitive Functionalized Polymeric-Nanometal Oxide Sensors for Potentiometric Determination of Ranitidine Hydrochloride

Two metal oxide nanoparticles, magnesium oxide nanoparticles (MgONPs) and aluminum oxide nanoparticles (Al2O3NPs), were synthesized from green sources, Salvia officials and Cuminum cyminum seed extract, respectively. These nanoparticles were used for construction of potentiometric enhancement sensors employed for the estimation of ranitidine hydrochloride (RNT) in authentic powder and commercial products. The electroactive substance ranitidinephosphotungstate (RNT-PT) was formed by combining RNT with phosphotungstic acid (PTA) in the presence of plasticizing material o-nitrophenyloctyl ether (o-NPOE). The outcomes showed that the enhanced MgO and Al2O3 nanosensors behaved linearly across the concentration ranges 1.0 × 10−9–1.0 × 10−2 and 1.0 × 10−10–1.0 × 10−2 mol L−1 , respectively. However, the conventional sensor (RNT-PT) displayed a linearity over 1.0 × 10−6–1.0 × 10−2 mol L−1 . Least square equations were calculated as EmV = (54.1 ± 0.5) log (RNT) + 762.33, EmV = (58.6 ± 0.2) log (RNT) + 696.48, and EmV = (52.2 ± 0.7) log (RNT) + 756.76 for enriched nanometal oxides modified and conventional sensors, respectively. The correlation coefficients of regression equations were 0.9997, 0.9995, and 0.9992 for the above suggested sensors, respectively. The recorded results showed excellent sensitivity and selectivity of the modified nanometal oxide sensors for the quantification of the analyzed drug in its authentic samples and commercial products.

نوع عمل المنشور
بحث علمي أصيل
اسم الناشر
Polymers
مزيد من المنشورات
publications

Due to massive industrial development, organic and inorganic wastes are very common in most industrial efuents from the pharmaceutical industry. Even in low concentrations, they are very dangerous…

بواسطة Nawal Alarfaj, Nawal Al Musayeib, Musarat Amina, Maha El‑Tohamy
2024
تم النشر فى:
Environmental Science and Pollution Research
publications

Recently, carbon dots (CDs) have been extensively investigated as potential tools for numerous applications. Modified lignin-based CDs have been synthesized and used in the field of drug detection…

بواسطة Fatemah Aldakhil, Nawal A. Alarfaj, Salma A. Al-Tamimi, Maha F. El-Tohamy
2024
تم النشر فى:
RSC Advances
publications

Recently, dual-mode techniques have garnered considerable attention and have been shown to be effective approaches for biomedical analysis and environmental monitoring.

بواسطة Fatemah Aldakhil, Nawal A. Alarfaj, Salma A. Al-Tamimi, Maha F. El-Tohamy
2024
تم النشر فى:
Journal of Fluorescence