Exploiting of Green Synthesized Metal Oxide Nanoparticles for Spectrophotometric Determination of Levofloxacin, Cephalexin, and Cefotaxime Sodium in Commercial Products
In this study, two metal oxide nanoparticles NiO and MnO2 were synthesized from
green sources Mentha spicata (M. spicata) extract and Malus domestica (M. domestica) peel extract,
respectively. The optical and physical properties of the synthesized nanoparticles were characterized
using spectroscopic and microscopic techniques. Simple, precise, and new spectrophotometric probes
were suggested for the determination of three cephalosporin antibiotics, including levofloxacin (LVX),
cephalexin (CPX), and cefotaxime sodium (CTX) in their pure form and commercial products. The
spectrophotometric detection of the selected drugs is based on the catalytic enhancement of NiO and
MnO2 nanoparticles (NPs) due to their unique optical properties. Linear relationships with main
correlation coefficients 0.999 were obtained at 0.1–20, 1.0–80, and 0.001–100 µg mL−1
for the three
drugs in the presence of NiONPs, whereas 0.01–60, 0.1–160, and 0.01–80 µg mL−1 were obtained in
the presence of MnO2NPs at absorption wavelengths 290, 262, and 235 nm for LVX, CPX and CTX,
respectively. The analytical methods were validated and successfully used for determination of the
instigated drugs in their bulk and commercial dosage forms.
Two metal oxide nanoparticles, magnesium oxide nanoparticles (MgONPs) and aluminum oxide nanoparticles (Al2O3NPs), were synthesized from green sources, Salvia officials
A facile, eco-friendly fluorescence approach based on the biogenic formation of zinc oxide
nanoparticles using the biomass of Plicosepalus curviflorus shoots was developed. The suggested…
In this study, two metal oxide nanoparticles NiO and MnO2 were synthesized from
green sources Mentha spicata (M. spicata) extract and Malus domestica (M. domestica) peel extract,
…