Dietary Protective Influence of Petroselinum crispum Nanoparticles on Some Biochemical, Reproductive Hormones, and Physiological Biomarkers of Female Clarias gariepinus (Burchell,1822) Exposed to Bisphenol A Toxicity
African catfish; biochemical parameters; bisphenol A; Petroselinum crispum nanoparticles; reproductivehormones
The currentstudyisapioneertrialtoverifytheeffectivenessof Petroselinum crispum (parsley) nanoparticles(PNPs)forfortifying
physiological andbiochemicalbiomarkersinfemaleAfricancatfish postexposuretobisphenolA(BPA)toxicity.Theaimofthis
experiment istoverifytheinfluence ofPNPsformitigatingserumhemato-biochemicalalterationsaswellasantioxidantenzyme,
and hormonalchangesinducedbyBPAtoxicityinthehepaticandovariantissues.Fishwereequallyallocatedintofourgroups:
group Iasacontrolwithoutanytreatments,groupIIreceivedacommercialdiet +PNPs (4g/kgdiet).IngroupIII, fish were
subjected to1/10LC50(BPA)(1.43 μg/L), whileingroupIV, fish got1/10LC50BPA(1.43 μg/L)+PNPs (4g/kgdiet)for60
consecutive days.ExposuretoBPAshowedmacrocytichypochromicanemiaandleukopenia,andanoticeableelevationinglucose,
alanine amino-transferase(ALT),aspartateaminotransferase(AST),ALP,urea,creatinine,cortisol,cholesterol,andtestosterone
(T) hormone.Furthermore,serumAchE,estradiol(E2),follicle-stimulatinghormone(FSH),luteinizinghormone(LH),globulin,
albumin, andtotalproteinsweresignificantly decreasedinaBPA-exposedgroup.Alternatively,activitiesofsuperoxidedismutase
(SOD), lipidperoxidation(LPO),andcatalase(CAT)werenotablyaugmentedinthehepatictissueandovariesoftheBPA-
supplemented fish. Whiletotalantioxidantcapacity(TAC)andreducedglutathione(GSH)levelsdecreasedintheequaltissuesof
exposed fish. PNPs-supplementeddietsincombinationwithBPAalleviateditsdestructiveeffectsonthetestedparameters.In
conclusion, theresultsprovedthatBPAisanendocrinehormonaldisruptorthatinducesimbalancesinbloodprofile, hepato–renal
indicators, andstressparameters,besidestheoccurrenceofoxidativedamageandreproductivedysfunction.Interestingly,PNPs
have aprotectiveroleinattenuatingBPAtoxicityandmodulatingallthemeasuredbiomarkers,aswellasimprovingthefertilityof
female Clarias gariepinus.
This study examined how dietary fennel essential oil (FEO) supplementation affected heat-stressed (HS) broiler
chickens' growth, economic efficiency, hematological and biochemical blood…
The currentstudyisapioneertrialtoverifytheeffectivenessof Petroselinum crispum (parsley) nanoparticles(PNPs)forfortifying
physiological andbiochemicalbiomarkersinfemaleAfricancatfish…
Elevated ambient temperature is the primary abiotic element that possibly diminishes production
and economic profitability in the chicken industry. The current study evaluated
the…