Foretinib (GSK1363089, FTB) is a multikinase inhibitor that inhibits multiple receptor tyrosine kinases, including vascular endothelial growth factor receptor-2 and mesenchymal–epithelial…
بواسطة
Mohammed M Alanazi, Hamad M Alkahtani, Abdulrahman A Almehizia, Mohamed W Attwa, Ahmed H Bakheit, Hany W Darwish
In this work, we present the synthesis and biological evaluation of novel series of diamide-based benzenesulfonamides 5a–h as inhibitors of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1)…
بواسطة
Mohamed A Abdelrahman, Wagdy M Eldehna, Alessio Nocentini, Silvia Bua, Sara T Al-Rashood, Ghada S Hassan, Alessandro Bonardi, Abdulrahman A Almehizia, Hamad M Alkahtani, Amal Alharbi, Paola Gratteri, Claudiu T Supuran
This course deals with the introduction to basic principles of pharmacology and receptor functions, the functional group properties, pharmacokinetics and receptor interactions in relation to…
The course concerns with the study of the principles and techniques of infrared (IR), mass spectrometry (MS), nuclear magnetic resonance (NMR), ultraviolet (UV) and fluorescence spectroscopy as…