The study investigated the anti-hyperglycemic potential of aqueous extracts of Emblica
officianalis fruit, Tamarix nilotica leaf and cinnamon sticks for six weeks on sterptozotocin
induced (70 mg/kg) diabetic obese rats compared to metformin as a standard drug. Six groups
were administered plant extracts at two doses (200 mg/kg b.wt, 400mg/kg b.wt) with two groups
as the positive and negative controls. Blood glucose, body weights, cholesterol, triglycerides, and
creatinine levels were assessed. All plant extracts doses; significantly (p≤0.001) reduced blood
glucose levels among diabetic rats in the fifth and sixth weeks except the group treated with the
lower dose of cinnamon. Body weights significantly increased during the fourth, fifth and sixth
weeks, being more pronounced in the plant treated diabetic groups compared to the diabetic
control and metformin group. Furthermore, all doses showed significant decrease (p≥0.05) in
serum glucose, cholesterol, triglyceride, and levels compared to the metformin, however, there
was no significant serum creatinine effect. The anti-diabetic potential of the plant extracts used
was dose-independent and there was no significant difference observed within the plant treated
groups. However, all the plant extract used proved better than metformin. This suggests a
marked anti-diabetic potential of the plant extracts attributed to their polyphenolic constituents.
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