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يزيد بن سليمان بن حمود الرثيع

Associate Professor

عضو هيئة تدريس

كلية الصيدلة
كلية الصيدلة, مبنى 23 الدور الاول, مكتب رقم 221

Medication complexity and affordability in use of time release antidepressants

While time-release (TR) formulations reduce medication complexity, their increased costs may compromise medication affordability.
This study examined how medication complexity and affordability affect the extent of access to TR formulations among adult patients
with depression. Study subjects consisted of adults (≥ 24 years old) with reported diagnoses of depression from the 2010 Medical
Expenditure Panel Survey (MEPS). Antidepressants that offer choices between TR vs. IR (immediate release) were selected. Factors
related to medication complexity and affordability were identified based on the Anderson’s model of health services utilization. A
multivariate logistic regression was used to examine the study hypotheses while controlling for complex survey sampling in MEPS.
A total of 625 working adults with depression had filled prescriptions with TR formulations about 60% of the time. Factors related
to medication affordability and complexity were significantly associated with the extent of access to TR antidepressant formulations.
Identification of those factors associated with the use of TR formulations would contribute to improving access as well as adherence
to antidepressant drug therapy. Clin Trans Sci 2014; Volume #: 1–8

Publication Work Type
Research Paper
Magazine \ Newspaper
Clinical and Translational Science
more of publication

Background: With the advent of the patient-centered care paradigm, it is important to examine what patients’ reports of
medication experience (PROME) mean to patient care. PROME available…

by Journal of Medical Internet Research


The relationship between medication adherence and treatment satisfaction has been consistently positive, however, this relationship has not been examined among older adults with…