Fond 111
Course objectives:
• General objectives:
The course is designed to:
Provide the student with a basic knowledge of the structure of cells, tissues and organs of the body.
Correlate the microscopic structure of individual tissue components and organs with their functions.
• Specific objectives:
At the end of the course, student should be able to:
Describe and identify the components and organelles of the cell.
Describe and identify the histological structure of the basic tissues of the body.
Describe and identify the histological structure of the organs of the body.
Correlate the structure and function of the cells, tissues and organs.
Learning format:
• Lectures
• Practical sessions
• Small Group Learning
Suggested References:
• L.P Gartner & J.L.Hiatt
W.B. Saunders Company, An imprint of Elsevier ,Philadelphia, Pennsylvania
The latest edition.
• DiFiore,s Atlas of Histology
V.P.Eroschenko, Lippincott Williams Wilkins, A Wolters Klumer Company
Philadelphia, New York, London, The latest edition.
Examinations:
• First semester:
Quiz 1: (5 marks)
First continuous assessment: written only (10 marks)
Second continuous assessment: comprehensive (30 marks)
Written examination: (20 marks)
Practical examination:(10 marks)
• Second semester:
Quiz 2: (5 marks)
Third continuous assessment: written only (10 marks)
Final examination: (40 marks)
Written examination: (30 marks)
Practical examination: (10 marks)
Practical Sessions:
• Demonstration of processing and staining of paraffin sections.
• Demonstration of electron micrographs of the following:
Cell nucleus:
Nucleolus, Heterochromatin, Euchromatin, Nuclear envelope,
Perinuclear cisterna, Nuclear pores.
• Cell cytoplasm:
Cell membrane
Mitochondria
Golgi apparatus
Rough endoplasmic reticulum
Smooth endoplasmic reticulum
Lysosomes
Centrioles
Cilia
Microvilli
• Epithelial membranes:
Simple squamous epithelium (e.g. endothelium)
Simple cuboidal epithelium (e.g. Thyroid gland)
Simple columnar epithelium with goblet cells (e.g. small intestine)
Pseudo-stratified ciliated columnar epithelium with goblet cells (e.g. nasal septum)
Non-keratinized stratified squamous epithelium (e.g. esophagus)
Keratinized stratified squamous epithelium (e.g. Skin)
Transitional epithelium (e.g. Urinary bladder)
• Epithelial glands:
Simple tubular gland (e.g. intestinal crypts of colon)
Simple branched tubular gland (e.g. fundic gastric glands)
Sebaceous gland (in skin)
Serous acini (e.g. Parotid salivary gland or Pancreas)
Mucous acini & mucoserous acini (e.g. Sublingual salivary gland)