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CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells

INTRODUCTION
Tumor microenvironment conferred by stromal (mesenchymal) stem cells (MSCs) plays a key role
in tumor development, progression, and response to therapy. Defining the role of MSCs in tumorigenesis is crucial for their safe utilization in regenerative medicine. Herein, we conducted comprehensive investigation of the cross-talk between human MSCs (hMSCs) and 12 cancer cell lines derived from breast, prostate, colon, head/neck and skin.

METHODS

Studying the Psychological Profile of Patients with Laryngopharyngeal Reflux.

Abstract

BACKGROUND/AIMS: 

Psychological factors have been claimed to play a role in the predisposition for laryngopharyngeal reflux (LPR) symptoms. The aims of this work were to study the relationship between psychological disorders and LPR and to investigate the effect of potential psychological disorders on patients' self-perception of reflux-related problems.

METHODS: 

Tutorials (NEW)

Please note that some of the answers in the tutorials are incorrect and were mentioned and clarified in the lectures.

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Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immune system through bone marrow transduction and immune reconstitution

T-cell receptor (TCR) with unique major histocompatibility complex (MHC)-unrestricted antigen-binding properties was isolated from a human T-cell clone specific for the tumor antigen MUC1. This TCR binds its epitope on the MUC1 protein without the requirement of processing and presentation. A single-chain Valpha/Vbeta/Cbeta (scTCR) was fused to a CD3 zeta (zeta) chain to allow expression on the surface of cells of the innate (granulocytes, macrophages, natural killer [NK] cells) as well as the adaptive (T and B cells) immune system.

302mkt

This course will enable students to learn fundamental concepts in Marketing Research (MR). Data sourcing and collection being the major task of MR, students can get to know types of data sources, data collection methods and instruments. The heart of the MR is Methodology, which equips with methods and designs to plan and implement and conduct successful experiments in social sciences area. The Analysis part deals with tools to tabulate and process the data. Finally it will enlighten them of how MR process to be organized in an understandable report format.
 

Examining job seekers’ perception and behavioural intention toward online recruitment: a PLS path modelling approach

Abstract: Electronic recruitment has become an essential practice among
competitive firms in various industries owing to the importance of human
resource capabilities toward building competitive positioning. The purpose of
this study is to examine the impact of information content qualities (ICQ),
vividness (VID), interactivity (INT), attractiveness and effectiveness (EFE),
search engine optimisation (SEO), website ranking (WER), and ease of
navigation (EN) on job seekers’ perception and behavioural intention (BI).

The effect of entrepreneurship orientation and learning orientation on SMEs’ performance: an SEM-PLS approach

Abstract: This study attempts to investigate the effects of entrepreneurial orientation and learning orientation on SMEs’ performance. A total of 200 SMEs from the electronic and electrical sector, and 250 SMEs from food and beverage industries were chosen randomly. The results of this study show that entrepreneurial orientation dimensions (innovativeness, proactiveness, and risk taking) and learning orientation have a significant relationship with SMEs’ performance.

201mkt first term (2015-2016)

This course is designed to help students learn about and apply the basic concepts and practices of modern marketing as they are used in a wide variety of settings: product and service firms, consumer and business markets, profit and nonprofit organizations, domestic and global companies, and small and large businesses.

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