Mysoon M. F. Al Ansari, PhD
Department of Botany and Microbiology
Faculty of Science, Women Students
Medical Studies & Sciences Sections
King Saud University.
Riyadh, Kingdom of Saudi Arabia
E-mail: myalansari@ksu.edu.sa
 
أستاذ مساعد. كلية العلوم، قسم النبات والأحياء الدقيقة، جامعة الملك سعود. فرع الدراسات الطبية للبنات. الرياض، المملكة العربية السعودية.
عالم مشارك كأستاذ ما بعد الدكتوراه (زمالة). قسم علم السرطان الجزيئي، مستشفى الملك فيصل التخصصي ومركز الأبحاث بالرياض. المملكة العربية السعودية.
المهام واللجان
-2016/2014 مقررة لجنة خدمة المجتمع, قسم الأحياء الدقيقة/ كلية العلوم. جامعة الملك سعود. الرياض
2015/2014 عضوة في لجنة التميز البحثي. جامعة الملك سعود. الرياض، المملكة العربية السعودية.
-2014/2013 مقررة لجنة التقييم والإعتماد, قسم الأحياء الدقيقة/ كلية العلوم. جامعة الملك سعود. الرياض
-2014/2013 عضوة في لجنة الأحياء الدقيقة لوضع العبء التدريسي بفرع قسم الأحياء الدقيقة/ كلية العلوم. جامعة الملك سعود. الرياض، المملكة العربية السعودية.--
- عضوة في المجموعة البحثية لأورام سرطان الثدي. مستشفى الملك فيصل التخصصي ومركز الأبحاث بالرياض. المملكة العربية السعودية.
- عضو  مشارك في الجمعية الأمريكية لأبحاث السرطان (AACR). الولايات المتحدة الأمريكية.
خدمة المجتمع
- مستشارة في أرامكو السعودية للتربية البيئية. الرياض، المملكة العربية السعودية.
- محكمة في الأولمبياد الوطني للإبداع العلمي، مسار البحث العلمي.
مؤتمرات وورش عمل
٢٠١٥/٢  رائدات التعليم الإلكتروني والتعلم عن بعد بترشيح من وزير التعليم العالي، مسار قيادي. مدة الدورة سنة كاملة،  تتضمن ثلاث أيام محاضرات تم تنظيمها في فندق الإنتركوتننتال بالرياض، ومحاضرات على الموقع الإلكتروني مع كتابة عدة تقارير
١٤٣٥/٢١ جمادى الثاني، دورة في تطوير ملف التدريس (٤ ساعات تدريبية). عمادة تطوير المهارات . جامعة الملك سعود. الرياض، المملكة العربية السعودية
٢٠١٤/٦م   تفهم الدرجات الخلوية في أورام الثدي على المستوى الجزيئي والوظيفي. مركز الأحياء للأورام، م
٢٠١٤/٦م   مؤتمر الأحياء الدقيقة بعد الثورة الجينية، مركز باستور، باريس فرنسا

إشراف طالبات الدراسات العليا

مناقشة وإمتحان طالبات ماجستير

١. حنان سليمان اليوسف،  كلية العلوم، قسم النبات والأحياء الدقيقة.
تاريخ الإصدار: ٨/٤/١٤٣٦، ١٩/٦/٢٠١٥
الدرجة العلمية: ماجستير
عنوان الرسالة: تقدير السموم الداخلية البكتيرية في مياه الشرب لتقييم السلامة الإحيائية للمياه في مدينة الرياض بالمملكة العربية السعودية.
Assessment of bacterial endotoxins in drinking water for evaluation water biosafety in Riyadh city, Saudi Arabia
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٢. رشا بنت محمد بن مفضي الزايد، ٤٣٠٢٠٤٠٠٠ كلية العلوم، قسم النبات والأحياء الدقيقة
تاريخ الإصدار: ١٤٣٦/٢٠١٥
الدرجة العلمية: ماجستير
عنوان الرسالة: العلاقة بين المحتوى الكمي للحمض النووي والنمط الوراثي لفيروس التهاب الكبد الوبائي ج باستخدام تفاعل البلمرة التسلسلي الوقتي الحقيقي كمؤشر دال للفيروس بالسعودية.
Correlation Between Viral Load of Hepatitis C Virus and Prevalance of HCV   as a Prognostic Indicator in Saudi RGenotypes using Real Time PC
٣. سجى أحمد الحفظي، كلية العلوم، قسم النبات والأحياء الدقيقة
تاريخ الإصدار: ١٤٣٥/٢٠١٤
الدرجة العلمية: ماجستير
عنوان الرسالة: إختبارات الحساسية لمضادات الفطريات على فطر الكانديدا في المملكة العربية السعودية.
Antifungul Susceptability of Clinical Candida Species Isolates, Saudi Arabia
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٤. غادة أحمد العامودي، كلية العلوم، قسم النبات والأحياء الدقيقة.
تاريخ الإصدار ١٤٣٥/٢٠١٤
عنوان الرسالة: التأثير المضاد للنشاط الفطري للزنك المؤكسد المحمل على الجزيئات النانونية
ticlesation of antifungul avtivituy of engineered zinc oxide nanoparِEvalu
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٥. الزهرة حمزة فدور مصيطفي، رقم جامعي  ٤٣١٣٠٣٩٩٩ كلية العلوم ، فسم النبات والأحياء الدقيقة.
الدرجة العلمية (ماجستير)/ تاريخ الإصدار: ٢١/٠١/١٤٣٥
عنوان الرسالة: التنوع الوراثي والتحليل البروتيومي لنبات تباع الشمس
 Genotypic and proteomics analysis of salt stressed sunflower (Helianthus Annulus)

تدريس مقررات طالبات البكالريوس ودراسات عليا

دراسات عليا:

•  حدق، علم البكتيريا المتقدم ٥٢١
•  حدق، موضوعات متخصصة        ٥٩١    
• حدق، الوراثة الجزيئية الميكروبية ٥٥٥
•  حدق، ميكانيكية الإصابة البكتيرية        ٥٢٢
•  حدق، كتابة خطة بحثية          ٥٩٦
• حدق، علم البكتيريا المتقدم   ٦٢١
• حدق، بكتريا ممرضة متقدم٦٢٢
• حدق، مضادات حيوية٦٢٣
• حدق، موضوعات متخصصة   ٦٩٢
•  حدق، رسالة٦٠٠

بكالريوس:

• ٢٦٠ حدق، علم الأحياء الدقيقة
• ٢٥١ حدق، وراثة بيولوجية 
• ٢٢١ حدق، علم الأحياء الدقيقة
• ٣٢١ حدق، علم فسيولوجي البكتيريا
• ٣٣٥ حدق، التحلل الحيوي
• ٤٦٠ حدق، البكتيريا الطبية
• ٤٦٣ حدق، مضادات حيوية
• ٤٩٣ حدق، تدريبات في ميكروبيولوجي المختبرات الصحية
• ٤٩٩ حدق، مشروع بحث

CURRANT STATUS

• Assistant Professor, Department of Botany and Microbiology. Faculty of Science. King Saud University. Women Students. Medical Studies & Sciences Sections. Riyadh, Saudi Arabia.
• Adjunct Scientist as Postdoctoral Fellow. Department of Cancer Biology & Experimental Therapeutics. KFSH&RC, Riyadh, Saudi Arabia.

EDUCATION
2012    Postdoc in Molecular Oncology. Department of Cancer Biology & Experimental Therapeutics. KFSH&RC. SA
2011    PhD in Molecular Genetics and Biology; King Saud University.
2010    Yale University Global Fellow in Infectious Diseases, King Saud University/ Yale University Global Student Exchange Program (Part of PhD Program); First Saudi Arabian Candidate, June 1st – August 1st.
Project Title: Pseudomonas Aeruginosa Twitching Motility, (Analysis of PilT on 0020 localization).
2002    Canadian Scholarship Program PhD; Immunology Courses, Communication Skills Course for the 21st Century and other courses, as a full-time PhD student. Queen’s University, Department of Microbiology and Immunology. Kingston, ON. Canada.
1997   Master of Science in Microbiology; King Saud University. Riyadh, Saudi Arabia
1993   BS in Biology (Micro-biology), King Abdul-Aziz University, Faculty of Science. Jeddah, Saudi Arabia.     
1989   Two Years in Medical School as BS, King Abdul Aziz University. Jeddah, Saudi Arabia.
 
CONTINEOUS EDUCATION
2015    April 14th to December 4th, eLearning Pioneers Female Faculty Development Program, OLC Learning, Leadership Track. Nominated by Ministry of Higher Education of Saudi Arabia.
EXPERIENCE
Teaching

• Undergraduates and Postgraduate Students Teaching
• Supervision and Examiner

·      Principal Supervisor of M.SC’s Graduate Students
Research
·      Postdoctoral fellow, DNA Repair and Apoptosis Section, Molecular Oncology Department, King Faisal Specialists Hospital and Research Centre (KFHRC). Riyadh, Saudi Arabia. (April 14th – July 5th 2011).
COMITIES MEMBERSHIP
·      Chief of Community Service Committee, (2014-2016), Microbiology Department, Science College, KSU.
·      Chief of Evaluation and Commitment Committee, (2014), Microbiology Department, Science College, KSU.
·      Chief of Teaching Load Committee, (2013). Microbiology Department, Science College, KSU.
·      Member in Excellence of Research Committee, Microbiology Department, Science College, KSU.
·      Associate member of American Association of Cancer Research (AACR).   
·      Consultant in Saudi Aramco Environmental Protection Program. Riyadh, Saudi Arabia.
 
PATENT
1.  Mysoon AlAnsari, M.S. AlSalhi, S. Devanesan,  Akram  Ahmed Alfuraydi. Green synthesis of silver nanoparticles using sesame (Sesamum indicum) oil cake and cytotoxicity study on MCF-7 Cell Line “USPTO  Docket  No 32809.55 : September 2016

BOOK TRANSLATION
Probiotics, Protection Against Infection. Author; Case Adams.
 
PUBLICATIONS

1. M. M. Al-Ansari and A. Abussekhra. ATR Protein Kinase in Breast Stroma Fibroblasts Represses Angiogenesis in Paracrine Manner. (In Preparation)
2. M. M. Al-Ansari, SF. Hendryani, and A. Abussekhra. Role of the ATR Protein Kinase in Tumor-Stromal Interactions in Breast Cancer. (In Preparation)
3. Mysoon Al-Ansari, Noorah Alkubais, P. Vijayaragavan, K. Murugan (2019) Antimicrobial potential of Streptomyces sp. to the Gram positive and Gram negative pathogens. J Infect Public Health. 2019 Nov - Dec;12(6):861-866. doi: 10.1016/j.jiph.2019.05.016.
4. Mysoon Al-Ansari, Noorah Alkubais, Kasi Gopinath, Viswanathan Karthika, Ayyakannu Arumugam, Marimuthu Govindarajan (2019). Facile and cost-effective Ag nanoparticles fabricated by Lilium lancifolium leaf extract:  Antibacterial and antibiofilm potential (2019) Journal of Cluster Science, Volume 30, Issue 4, pp 1081–1089. DOI: 10.1007/s10876-019-01569 Q3
5. Mysoon Al-Ansari, L. A. Al-Humaid, P. Vijayaraghavanb B. Ravindran S. W. Chang. Agastian, M. A. Rathi B. Balamuralikrishnan (2019). Identification of phytochemical components from Aerva lanata (Linn.) medicinal plants and its in-vitro inhibitory activity against drug resistant microbial pathogens and antioxidant properties. Saudi Journal of Biological Sciences, Vol.26:1129-1133 https://doi.org/10.1016/j.sjbs.2019.02.010. IF; 3.24 (Q1)
6. Akram A. Alfuraydi, Sandanasamy Devanesan, Mysoon Al-Ansari, Mohamad S. AlSalhi Amirtham J. Ranjitsingh  (2019) Eco-friendly green synthesis of silver nanoparticles from the sesame oil cake and its potential anticancer and antimicrobial activities. Journal of Photochemistry & Photobiology, B: Biology 192 (2019) 83–89. IF; 3.165 (Q1)
7. Al-Ansari, M. M., & Aboussekhra, A. (2018). ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts. Oncotarget, 9(78), 34681-34690. doi:10.18632/oncotarget.26159. IF; 5.168 (Q1)
8. Siti-Fauziah Hendrayani, Bothaina Al-Harbi, Mysoon M. Al-Ansari, Gabriela Silva, Abdelilah Aboussekhra (2016). The Inflammatory/Cancer-Related IL-6/STAT3/NF-κB Positive Feedback Loop Includes AUF1 and Maintains the Active State of Breast Myofibroblasts. Oncotarget; Vol. 7, No.27:41974-41985. (Q1)
9. Mysoon M. Al-Ansari, and Abdelilah Abussekhra (2015). MiR-146-5p mediates p16-dependent repression of IL-6 and suppresses paracrine procarcinogenic effects of breast stromal fibroblasts. Oncotarget; Vol. 6, No. 30:30006-30016 (Q1)
10. Mysoon M. Al-Ansari, and Abdelilah Abussekhra (2014). Caffeine Mediates Sustained Inactivation of Breast Cancer-Associated Myofibroblasts via Up-Regulation of Tumor Suppressor Genes. PLoS ONE 9(3): e90907. doi:10.1371/journal.pone.0090907. IF; 2.766 (Q1)
11. M. M. Al-Ansari, SF. Hendryani, A. Tulbah, T. Al-Tweigeri, A. I. Shehata, and A. Aboussekhra. (2012). p16INK4A Represses Breast Stromal Fibroblasts Migration/Invasion and their VEGF-A-Dependent Promotion of Angiogenesis Through Akt/mTOR/HIF-1α Pathway Inhibition. Neoplasia, Vol. 14, No. 12:1269–1277. IF; 4.994 (Q1)
12. M. M. Al-Ansari, SF. Hendryani, A.I. Shehata and A. Abussekhra. (2012). P16INK4A represses the paracrine tumor-promoting effects of breast stromal fibroblasts. Oncogene, Nature. 32:2372. 10. 1038/onc.2012.270. IF; 6.854 (Q1)
13. M. M. AL Ansari and R. Al Somm. Production, Purification and Characterization of Lipase Produced From Bacillus sp. II Group Grown on Sesumum Indicum Litters. 2003. R. J. Med. Res. Inst.–Alex. Univ. 24 (2 Supp.): 39-53.

PRESENTATIONS
Oral:
2019 Microbiome; Gut Microbiota or More?
2018 How to Write a Proposal For PhD & Master Students (Workshop). Targeting Postgraduate Students From Deferent Specialties. Postgraduate Building, Training Centre, 27.06.1439H
2017  MiR-146-5p Mediates IL-6 and Suppresses Paracrine Procarcinogenic Effects of Breast Stromal Fibroblasts. Programme: Research Collaboration Workshop: Genomics and Precision Medicine 22 – 23 March. King Saud University – Riyadh - KSA
2015    Research Design and Methods. Research Centre, Girls Campus, King Saud University. Riyadh, Saudi Arabia.
2014    Role of IL-6 in the Pro-Carcinogenic Effects of Breast Stromal Fibroblasts. Invasive Breast Cancer: New Molecular Insights and Translational Potentials. January 8th. King Faisal Specialist Hospital and Research Centre. Riyadh, Saudi Arabia.
2013    How to Search and Read a Scientific Journal. September 16th. Post-graduate program. Research Center Building, King Saud University. Riyadh, Saudi Arabia.
2012   Role of Caffeine and p16INK4a in Suppressing the Pro-Angiogenic Paracrine Effects of Breast Cancer-Associated Fibroblasts. The 11th Annual Research Report, April 16th – 17th. King Faisal Specialist Hospital and Research Centre. Riyadh, Saudi Arabia.
2012    Role of p16INK4A and Caffeine in Suppressing the Expression/Secretion of IL-6 and the Pro-carcinogenic Effects of Breast Cancer-Associated Fibroblasts. M. M. Al-Ansari, SF. Hendrayani and A. Aboussekhra. November 13th-17th, CSH Asia/ICMS Joint Conference on Tumor Microenvironment. Suzhou, China.
2011    The 10th Annual Research Report, April 4th. Role of the Tumor Suppressor p16 Protein in Tumor-Stromal Interaction in Breast Cancer. King Faisal Specialist Hospital and Research Centre. Riyadh, Saudi Arabia.
Poster:
2014    M. Al Ansari, Abdelilah Aboussekhra, Down-regulation of p16INK4a inhibits miR-146b-5p and modulates IL-6 in breast stromal fibroblasts. Henry B. Gonzalez Convention Center, December 9-13 Annual Breast Cancer Symposium. San Antonio, Texas, USA
2013    M. Al Ansari, Abdelilah Aboussekhra, Caffeine normalizes breast stromal fibroblasts and suppresses their pro-carcinogenic effects. Cancer Res;73(8 Suppl): 4886. doi:10.1158/1538-7445.AM2013-4886
            Presented at AACR Annual Meeting April 6th-10th 2013. Washington DC, USA
2011    A. Aboussekhra, MM Al-Ansari, S-F Hendrayani, and T. Al-Tweigeri Role of the ATR Protein Kinase and Curcumin in Tumor-Stromal Interactions in Breast Cancer. Cancer Res;70(24 Suppl):Abstract nr P4-05-02
Presented at 33rd Annual Breast Cancer Symposium, December 8th -12th 2010, San Antonio, Texas, USA.
2011    M. M. Al-Ansari, SF. Hendrayani, A. Tulbah and A. Aboussekhra, p16INK4A Represses Breast Stromal Fibroblast Activation and the Related Paracrine Tumor Promoting Effects. November 3-6, Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy. American Association of Cancer Research. Orlando, FL, USA.
AWARDS
2017    Best publication award for “The Inflammatory/Cancer-Related IL- 6/STAT3/NF-κB Positive Feedback Loop Includes AUF1 and Maintains the Active State of Breast Myofibroblasts”. 17th Research center annual report 2016 from 19-20 April. Prince Salman Auditorium, KFSH&RC, Riyadh, Saudi Arabia.
2015    Best publication award for “MiR-146-5p mediates p16-dependent repression of IL-6 and suppresses paracrine procarcinogenic effects of breast stromal fibroblasts”. Research center annual report 2015 from 13-14 April. Prince Salman Auditorium, KFSH&RC, Riyadh, Saudi Arabia.
 
2012    Best publication award for “p16INK4A Represses the paracrine tumor-promoting effects of breast stromal fibroblasts”. Research center annual report 2012 from 20-21 Jun. Prince Salman Auditorium, KFSH&RC, Riyadh, Saudi Arabia.
 
2012    Best publication award for “p16INK4A represses breast stromal fibroblast migration/invasion and their VEGF-A dependent promotion of angiogenesis through Akt inhibition”. Research center annual report 2012 from 20-21 Jun. Prince Salman Auditorium, KFSH&RC, Riyadh, Saudi Arabia
 
CONFERENCES, WORKSHOP AND LECTURES ATTENDED
2018 Integrative Molecular Epidemiology Workshop: Bridging Cancer Biology and Precision Medicine, AACR. Westin Copley Place Boston, Massachusetts, USA. July 9-13.
2016    Applying the Quality Matters Rubric (APPQMR), Quality Matters Online US Program. October 2, 2015.
2015    July 20-30th, Exploration and Hands-on Training on the Practice of eLearning at US Institutions. TUFT University and Marriot-Cambridge. Boston, USA.
2015    May 12-16th, Biology of Cancer: Microenvironment, Metastasis & Therapy. Cold Spring Harbor, New York, USA.
2014    June 24th, EMBO Conference of Microbiology After the Genomics Revolution. Pasteur Institution, Paris, France.
2014    June 3rd. Understanding Histological Grade in Breast Cancer at Molecular and Functional Level. Possible Utility in Patient Stratification and Management. Dr.Sheikh Sayeed, Department of Cancer Biology, Thomas Jefferson University, Pheladelpia PA. Held by; KFSH&RC, Riyadh, Saudi Arabia.
2014    April 21st, Developing a Teaching Portfolio. Deanship of Skills Development, King Saud University. Riyadh, Saudi Arabia.
2014    April 16-17, Annual Report of Research Centre. King Faisal Specialist Hospital and Research Centre. Riyadh, Saudi Arabia.
2013    July 7-10, 14th International Tumor Necrosis Factor (TNF) Conference. Quebec City, Quebec, Canada.
2013    April 6-10, AACR Annual Meeting 2013. Washington DC, USA
2010    July 12-23, IMED 645 Introduction to Biostatistics in Clinical Investigation. Investigative Medicine Program, Graduate School of Arts and Science, Yale university. New Haven, CT, USA.
2010    April 5-9, International Breast Cancer Conference, Riyadh, Saudi Arabia.
2009    October 20-24, AACR 5th International Conference, on Tumor Microenvironment: Progression, Therapy & Prevention. Versailles, France.
2008    March 16-19, AACR International Conference. Advances in Cancer Research: From the Laboratory to the Clinic. King Hussein Bin Talal Convention Center, Dead Sea, Jordan.
APPLIED SKILLS
Human tissue and microbial culture, Cloning, RNA extraction, RT-RCR, Real Time RT-PCR, Western Blot, Protein extraction, ELISA, Transfection, Zymography, UV and Gama Irradiation, Human and animal dissection (anatomy), Histology, Immunonoflourecent and Immunonohestochemistry, Fluorescent microscopy, Confocal microscopy
 
EXTRA ACTIVITIES
2014    May 14th, Attended the closing ceremony for 2014 of Aramco Environment Protection as Guest of Honor, Ritz Carlton Hotel. Riyadh, Saudi Arabia.
2014    Feb. 6th Scientific Research Examiner and Judge, Final of National Olympiad for Scientific Creativity, Ebdaa. Al Jawdah School, Riyadh, Saudi Arabia
2013    March18th Scientific Research Examiner and Judge, Final of National Olympiad of Scientific Creativity, Ebdaa. Riyadh, Saudi Arabia
2013    February18th Scientific Research Examiner and Judge, National Olympiad of Scientific Creativity, Ebdaa. Riyadh, Saudi Arabia
2012    April14th Scientific Research Examiner and Judge, National Olympiad of Scientific Creativity, Ebdaa. Riyadh, Saudi Arabia
2012    Feb.18th. Scientific Research Examiner and Judge, National Olympiad of Scientific Creativity, Ebdaa. Hayil, Saudi Arabia.
2011    Feb.14th. Participating as a Judge in the National Olympiad for Scientific    Creativity, Ebdaa. Hayil, Saudi Arabia.
2010    Basic Cardiac Life Support Provider, According to the Standards and Guidelines of the American Heart Association. CPR Education Centre, Riyadh Military Hospital
1999    Decoration, dress making and design. Diploma with highest honors in Dress making and Design; International correspondence schools, Montreal, Quebec, Canada
1994   Introduction to Computer & DOS Course; Queen Effat University, Jeddah K.S.A. In Cooperation with the American University in Cairo
1993    Dental Clinic, King Abdul-Aziz University, Six months training,
1993    One month training in Medical Bacteriology lab, King Abdul-Aziz University Hospital
 
REFERENCES

• Abdelilah Aboussekhra, PhD

Head of DNA Repair & Apoptosis Research Unit, Molecular Oncology Department, King Faisal Specialist Hospital & Research Center, BMC # 03-66, P.O. BOX; 3354, Riyadh 11211, Kingdom of Saudi Arabia

• Michael Capillo, M.D.

Professor of Pediatrics, Microbial Pathogenesis and Public Health Director, Program in International Child Health Director. Yale University.
Yale Child Health Research Centre R 464 Congress Avenue, New Haven, CT. 06520, Phone: 203-737-4320 Fax: 203-737-5972
E-mail: michael.cappello@yale.edu