Background: Etiologies of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are heterogeneous. We phenotyped severe AECOPD based on molecular pathogen…
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Nawaf M Alotaibi, Virginia Chen, Zsuzsanna Hollander, Jonathon A Leipsic , Cameron J Hague, Darra T Murphy, Mari L DeMarco, J. Mark FitzGerald, Bruce M McManus, Raymond T Ng, Don D Sin
Rationale: Lung dysbiosis promotes airway inflammation and decreased local immunity, potentially playing a role in the pathogenesis of acute exacerbations of COPD (AECOPD). We determined the…
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Fernando Sergio Leitao Filho, Nawaf M Alotaibi, David Ngan, Sheena Tam , Julia Yang, Zsuzsanna Hollander, Virginia Chen, J. Mark FitzGerald, Corey Nislow, Janice M leung, SF Paul Man, Don D Sin
Introduction: The use of beta-blockers in chronic obstructive pulmonary disease (COPD) is controversial, primarily due to concerns that they may worsen lung function and attenuate bronchodilator…
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Nawaf M Alotaibi, Fernando Sergio Leitao Filho, Kei Yamasaki, David A Ngan, Don D Sin