EXAM MODEL

• Course: PHL 322

KING SAUD UNIVERSITY, PHL 451 second semester, 1423/1433

You have 30 questions. All questions have to be answered. Select the single best answer or completion

 

1. 1.     1.   All are true about strychnine, except:
2. A.   It is the main constituent of opium
3. B.   Its site of action is the spinal cord
4. C.   It is a CNS stimulant
5. D.   It is not used clinically
6. E.   It causes symmetric convulsions

 

1. 1.     2.   Central actions of amphetamine include the following, except:
2. A.   Increased mental performance
3. B.   Psychosis
4. C.   Increased respiration
5. D.   Appetite suppression
6. E.   Attention

 

1. 1.     3.   Amphetamine causes:
2. A.   Pupillary dilatation
3. B.   Physical and psychological dependence
4. C.   Constipation
5. D.   Only A and B
6. E.   Only B and C

 

1. 1.     4.   Amphetamine is indicated in
2. A.   Asthma and chronic bronchitis
3. B.   Narcolepsy
4. C.   Obesity
5. D.   Myocardial infarction
6. E.   All of the above

 

1. 1.     5.   A glycine antagonist from the following is
2. A.   Piracetam
3. B.   Picrotoxin
4. C.   Captagon
5. D.   Pentazocine
6. E.   Strychnine

 

 

 

 

 

 

1. 1.     6.   Piracetam is:
2. A.   Analgesic
3. B.   Cortical stimulant
4. C.   Nootropic
5. D.   All of the above
6. E.   Only B and C

 

1. 1.     7.   Prolonged use of high doses of amphetamine may cause :
2. A.   Liver damage
3. B.   nephrotoxicity
4. C.   Both
5. D.   Neither
6. E.   Only A

 

1. 1.     8.   The mode of action of theophylline is:
2. A.   Inhibition of prostaglandin synthesis in the CNS
3. B.   Inhibition of prostaglandin synthesis in the periphery
4. C.   Inhibition of prostaglandin release  in the CNS and the periphery
5. D.   All of the above
6. E.   None of the above

 

1. 1.     9.   One of the following statements is correct for doxapram
2. A.   It is contraindicated in gastritis
3. B.   It  treats gout, when used in low doses
4. C.   It  is a spinal cord stimulant, when used in large doses
5. D.   Prolonged use of it  may precipitate dependence
6. E.   It is a useful analeptic
7. 1.     10.  One of the following is an inhibitory neurotransmitter in the brain
8. A.   Noradrenaline
9. B.   Dopamine
10. C.   GABA
11. D.   Glycine
12. E.   Glutamate

 

1. 1.     11.  Cortical stimulants include the following, except:
2. A.   Captagon
3. B.   LSD
4. C.   caffeine
5. D.   Piracetam
6. E.   Pentylene tetrazole

 

1. 1.     12.  The major adverse reaction of amphetamine from the following is:
2. A.   Bone marrow depression
3. B.   Drowsiness; confusion and agitation in the elderly.
4. C.   Water intoxication (nausea, vomiting, abdominal pain).
5. D.   Ataxia
6. E.   Insomnia

 

1. 1.     13.  Indications for sodium channel blockers are the following, except:
2. A.   Local anesthesia
3. B.   Epilepsy
4. C.   Hypertension
5. D.   Dysrhythmias
6. E.   Neuropathic pain

 

1. 1.     14.  An inhibitor of GABA function from the following is:
2. A.   Khat
3. B.   Delta-9-tetrahydrocannabinol
4. C.   Picrotoxin
5. D.   Fenfluramine
6. E.   Doxapram

 

1. 1.     15.  Glutamate is:
2. A.   Used to treat epilepsy
3. B.   May induce aplastic anaemia and acute hepatic failure.
4. C.   Excitotoxic, if released in high amounts
5. D.   An antagonist at NMDA receptor
6. E.   All of the above