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Professor Gamal A. El-Hiti

Professor

King Saud University

كلية العلوم الطبية التطبيقية
Building 24; Room 2213

Catalytic, Green and Regioselective Friedel-Crafts Acylation of Simple Aromatics and Heterocycles Over Zeolites

El-Hiti, Gamal A. . 2015

Traditional Friedel-Crafts acylation reactions of aromatics suffer from low regioselectivity towards para- or more linear isomers and usually require stoichiometric quantities of Lewis acids, which are hydrolysed to produce toxic waste during aqueous work-up. Zeolites can catalyse and enhance the selectivity in Friedel-Crafts acylation reactions of simple aromatics and heterocycles. For example, high regioselectivity was achieved in acylation of aromatic ethers, aromatic hydrocarbons and heterocycles over zeolites. This brief review highlights the importance of zeolites to enhance the regioselectivity in Friedel-Crafts acylation reactions.

Publication Work Type
Review Article
Volume Number
19
Issue Number
7
Magazine \ Newspaper
Current Organic Chemistrty
Pages
585-598
more of publication