Effects of dietary supplementation with zinc oxide or selenium nanoparticles and their combination on rabbit productive performance, nutritional and physiological responses
Rabbit; nanotechnology; minerals; digestibility; blood biochemical parameters
This research investigated how supplementing growing rabbits with zinc oxide nanoparticles
(Nano-ZnO) and selenium nanoparticles (Nano-Se) impacts their growth performance, digestibility,
blood biochemistry, and liver mineral content. The study utilised 40 male and 40 female
New Zealand White rabbits, all 30 days old, with an average weight of 720 ± 6 g. Rabbits were
divided into four treatment diets with 10 replicates of two rabbits each (one male and one
female) for 60 days. The diets comprised of 1) control diet, 2) control diet þ 40 mg/kg Nano-
ZnO, 3) control diet þ 0.6 mg/kg Nano-Se, and 4) control diet þ 40 mg/kg Nano-ZnO þ 0.6 mg/
kg Nano-Se. Results showed that dietary Nano-ZnO and Nano-Se in single or combination
improved (p<0.05) the growth performance, carcase yield, crude protein, and ether extract
digestibility compared with the control group. Rabbits received Nano-ZnO and Nano-Se alone or
in mixture showed lower (p<0.05) abdominal fat and serum levels of cholesterol, alanine aminotransferase
(ALT), aspartate aminotransferase (AST), creatinine, and urea activities than the
control. The addition of Nano-ZnO, Nano-Se, or their combination did not affect the concentrations
of zinc or selenium in the livers of male and female rabbits. In conclusion, dietary supplementation
of Zinc oxide and Selenium nanoparticles alone or in combination improved growth
performance and nutrient digestibility of male and female rabbits.
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