Dr. Hussain is internationally recognized for his expertise in Hansen Solubility Parameters (HSPiP), computational and thermodynamic models for solubility studies (including Van’t Hoff and Apelblat models) of poorly soluble drugs, QbD-enabled optimization for identifying critical material and process variables, and the development of environmentally sustainable processes and analytical methods. In pharmaceutics, nanomedicine has been extensively explored as a drug delivery system, serving as an alternative therapeutic carrier with well-informed patient outcomes through a technology transfer approach from laboratory research to clinical application. A deeper understanding of GastroPlus-based simulations enables accurate prediction and correlation of in vitro and in vivo data in appropriate animal models and humans, enhancing insights into pharmacokinetics and pharmacodynamics (IVIVC).
He has authored approximately 150 publications, including 18 book chapters and more than four copyrights registered with the Indian government. His work has an H-index of 29 on Google Scholar, with over 2,700 citations. He has supervised five Master's students, ten undergraduate students, and one PhD candidate, in addition to managing three research projects. He serves on the editorial board of more than four journals and reviews for over 30 peer-reviewed journals. Actively engaged in research, he has played a key role in various projects, and his team has presented numerous conference papers.
areas of expertise
Nanomedicine as drug delivery; HSPiP and GastroPlus enabled predictive solubility and pharmacokinetics studies; Environmentally sustainable analytical method development and validation; Biocompatible polymer and natural lipids explored for oral, parenteral, and topical drug delivery system; AI-based predictive studies (Machine learning and deep learning)