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Dr. Asma Abdullah M Alothman

Associate Professor

Associate Professor of Chemistry

كلية العلوم
Building no. 5, T179
publication
Journal Article
2020

Synthesis, characterization, density functional theory, thermal, antimicrobial efficacy, and DNA binding/cleavage studies of Cu( II), Cr(III), Fe(III), Ni(II ), Co(II), Zn(II), and Pt(IV) complexes with a derivative of 2‐hydroxyphenoxymethylfuran‐5‐carbal

M., Al‐Mohaimeed, Amal . 2020

In this study, Seven new complexes incorporating (E)-2-(((5-([2-hydroxyphenoxy]methyl)furan-2-yl)methylene)amino)phenol derived from 2-hydroxyphenoxymethylfuran-5-carbaldehyde and 2-aminophenol have been synthesized using Cu(II), Cr(III), Fe(III), Ni(II), Co(II), Zn(II), and Pt(IV) metal salts. Thermal measurements, molar conductance, magnetic moment, elemental analyses, spectral (IR, UV–Vis, 1H nuclear magnetic resonance (NMR), ESR, Mass), were used to characterize insulated solid complexes. The thermogravimetry (TG) and differential thermoanalysis (DTA) of the complexes were carried out in the range of 30–900°C. Magnetic susceptibility and electronic spectral data, as well as quantum chemical calculations, reveal the square planar geometry for Ni (II) complex, square planar/octahedral geometry for Cu (II) complex, while Co(II), Zn(II), Cr(III), Fe(III), and Pt (IV) complexes are octahedral geometry. Density functional theory (DFT) studies revealed that geometries of metal complexes and Schiff base were entirely optimized in relation to use energy by 6–31 + g (d,p) basis set. The complexes show a well-defined crystal system indicated by a powder-X-ray diffraction pattern. The scanning electron microscope showed complexes were nanocrystalline in nature, in addition to the interaction of the complexes with calf thymus CT-DNA, which was investigated via the UV–visible absorption method. Therefore, the DNA cleavage activity by the H2L ligand and its metal complexes was performed. Finally, the synthesized complexes were tested for their in-vitro antimicrobial efficacy.

Magazine \ Newspaper
Journal of the Chinese Chemical Society
more of publication
publications

Preconcentration for on-site detection or subsequent determination is a promising technique for selective sensing explosive markers at low concentrations.

by Yusuf, K., O. Shekhah, S. Alharbi, A. A. Alothman, A. S. Alghamdi, R. M. Aljohani, A. LOthman ZA, and M. Eddaoudi.
2023
publications

Chemical environment and precursor-coordinating molecular interactions within a perovskite precursor solution can lead to important implications in structural defects and crystallization kinetics…

by Yang, B., J. Suo, D. Bogachuk, W. Kaiser, C. Baretzky, O. Er-Raji, G. Loukeris, A. A. Alothman, E. Mosconi, M. Kohlstadt, U. Wurfel, F. De Angelis, and A. Hagfeldt
2024
publications

Photocatalytically active heterojunctions based on metal halide perovskites (MHPs) are drawing significant interest for their chameleon ability to foster several redox reactions. The lack of…

by Tedesco, Costanza, Luca Gregori, Angelica Simbula, Federico Pitzalis, Andrea Speltini, Francesca Merlo, Silvia Colella, Andrea Listorti, Edoardo Mosconi, Asma A. Alothman, Waldemar Kaiser, Michele Saba, Antonella Profumo, Filippo De Angelis, and Lorenzo M
2024