A liquid chromatography-mass spectrometry (LC/MS) assay method was developed for the quantification of PSC 833 in rat plasma, using amiodarone as internal standard (IS).
بواسطة
Binkhathlan Z, Somayaji V, Brocks DR, Lavasanifar A
Valspodar is a P-glycoprotein inhibitor widely used in preclinical and clinical studies for overcoming multidrug resistance. Despite this, the pharmacokinetics of valspodar in rat, a commonly used…
بواسطة
Binkhathlan Z, Hamdy DA, Brocks DR, Lavasanifar A
The aim of this study was to assess the potential of polymeric micelles to solubilize valspodar and modify its pharmacokinetics following intravenous and oral administration in rat.
بواسطة
Binkhathlan Z, Hamdy DA, Brocks DR, Lavasanifar A
The course provides basic and application of Nanotechnology in the area of Drug Delivery. It focuses on the main operations that take place to make nanoparticles. These operations include top-down…
The course provides a general overview of polymers and their use in the design of drug delivery systems (DDS). The course will introduce the students to the different types of polymers as well as…