LDL drive the Polarized secretion of endothelial fibronectin through Syntaxin-4 and Syntaxin-6
The proteins secreted in response to LDL have established roles in the progression of atherosclerosis, including fibronectin and MMP1. My work demonstrates a novel secretory response to lipoprotein, which leads to release of pro-atherogenic, pro-inflammatory regulators.
The proteins secreted in response to LDL have established roles in the progression of atherosclerosis, including fibronectin and MMP1. My work demonstrates a novel secretory response to…