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أ.د رويدا عبدالحكيم عبدالجابر عبدالحكيم

Professor

أستاذ بقسم علم الحيوان

كلية العلوم
مبني 5، الدور الثالث، مكتب رقم 105
المنشورات
مقال فى مجلة
2023

Biosynthesized Nanosilver from Ginger Extract Exhibits Antioxidant and Hepatic Responses during Eimeria papillata Infection

Although several anticoccidial medications have long been used to prevent coccidiosis, their adverse effects necessitate the use of alternative control methods. In this study, Eimeria papillate was used to infect the mouse jejunum, and the response of the liver to induced coccidiosis on treatment with nanosilver synthesized from Zingiber officinale (NS) and the reference anticoccidial drug amprolium was compared. Mice were infected with 1000 sporulated oocysts to induce coccidiosis. NS was able to inhibit the sporulation of E. papillate by approximately 73%, and also, the NS treatment improved the liver function in mice, as proven by lower levels of the liver enzymes AST, ALT, and ALP. Furthermore, treatment with NS improved the parasite-induced liver histological injury. Also, glutathione and glutathione peroxidase levels increased following treatment. Moreover, the concentrations of metal ions, Fe, Mg, and Cu, were studied, where only the Fe concentration was affected after treatment of the E. papillate-infected mice with Bio-NS. The presence of phenolic and flavonoid compounds in NS is thought to be responsible for its positive effects. Overall, the current study found that NS outperformed amprolium in E. papillata-induced mice.

اسم الناشر
ACS Omega
مزيد من المنشورات
publications

Due to the presence of different parasite taxa and other disease-causing agents, all fish species are extremely prone to dangers.

بواسطة Rewaida Abdel-Gaber, Masheil Alghamdi, Saleh Al Quraishy, Esam M. Al-Shaebi, Manal F. Elkhadragy, Saeed El-Ashram, Mohamed A. Dkhil
2023
تم النشر فى:
Animals
publications

Eimeriosis, an infection with Eimeria spp. that affects poultry, causes huge economic losses. Silver nanoparticles (AgNPs) have antibacterial and antifungal properties, but their action against…

بواسطة Mohamed A. Dkhil, Felwa A. Thagfan, Mostafa Y. Morad, Esam M. Al‑Shaebi, Sherif Elshanat, Amira A. Bauomy, Murad Mubaraki, Taghreed A. Hafiz, Saleh Al‑Quraishy, Rewaida Abdel‑Gaber
2022
تم النشر فى:
Environmental Science and Pollution Research
publications

Apicomplexan parasites, especially Eimeria sp., are the main intestinal murine pathogens, that lead to severe injuries to farm and domestic animals. Many anticoccidial drugs are available for…

بواسطة Tahani Al-Otaibi, Maysar Abu Hawsah, Ghada Alojayri, Mohammed M. Mares b, Hossam M.A. Aljawdah, Saleh N. Maodaa, Esam M. Al-Shaebi, Mohamed A. Dkhil, Felwa A. Thagfan, Saleh Al-Quraishy, Rewaida Abdel-Gaber
2023
تم النشر فى:
Parasitology International