Endothelial nitric oxide synthase gene polymorphisms (894G > T and -786T > C) and risk of coronary artery disease in a Saudi population
Abstract
Background and aims: Endothelial nitric oxide synthase gene polymorphisms, either independently or through gene environmental interactions, are associated with cardiovascular diseases in multiple ethnic populations. However, no information is available with regard to such associations in a Saudi population despite a high incidence of cardiovascular abnormalities. We studied the associations of 894G>T and -786T>C polymorphisms of endothelial nitric oxide synthase gene with coronary artery disease in Saudi population.
The role of maternal gut hormones in normal pregnancy: fasting plasma active glucagon-like peptide 1 level is a negative predictor of fetal abdomen circumference and maternal weight change
Abstract
Objective: Maternal weight in pregnancy contributes to a glycemic environment that affects fetal growth. Gut peptides (glucagon-like peptide 1 (GLP1), glucose-dependent insulinotropic peptide (GIP), ghrelin, and peptide YY (PYY)) have been related to insulin sensitivity and secretion, weight control, and adipose tissue metabolism. This study aimed at examining the associations of gut hormones during pregnancy with maternal glucose homeostasis, maternal weight, and fetal growth.
Relationship between resistin and aPAI-1 levels with insulin resistance in Saudi children
Abstract
Background: Association of resistin with insulin resistance (IR) in humans is still controversial and few studies have investigated the association of plasminogen activator inhibitor-1 (PAI-1) with IR in children. The purpose of the present study was therefore to evaluate serum levels of resistin and active PAI-1 (aPAI-1) in Saudi children and their association with the various obesity-related complications.
Technology-based multi-tiered building diagnosis framework
Purpose
A building deteriorates over time due to aging, wear and tear, and inadequate maintenance. Building diagnosis requires a sound knowledge of engineering, building defects, and detection tools to assess the condition of a building. The physical deterioration of a building reduces its ability to perform its intended function, while environmental deterioration influences the comfort and health of building occupants. This study presents a multi-tiered framework for the inspection of building elements and the environmental conditions of a building.