Introduction to inorganic reaction mechanisms, soft and hard acids and bases, Neuclophilic substitution reactions at four-coordinate Site, Mechanism of OxidationReduction reactions, Bio-inorganic Chemistry including: Non red-ox metallic enzymes, Oxygen carriers and the weight of oxygen proteins, Proteins ofthe hemoglobin, Nitrogen fixation and sulfur, iron proteins, Heavy metal ion storage, Metals and non-metals in medicine and biologicalsystem.