How can the orthopedic surgeon ensure optimal vitamin D status in patients operated for an osteoporotic fracture?

مقال فى مجلة
نوع عمل المنشور
دكتوراة
مدينة النشر
Geneva Univ Hosp, Serv Bone Dis, Geneva, Switzerland
رابط النشر على الانترنت
اسم الناشر
Osteoporos Int
مجلة/صحيفة
OSTEOPOROSIS INTERNATIONAL
رقم الانشاء
10
رقم المجلد
32
الصفحات
1921
ملخص المنشورات

Abstract
In this narrative review, the role of vitamin D deficiency in the pathophysiology, healing of fragility fractures, and rehabilitation is discussed. Vitamin D status can be assessed by measuring serum 25(OH)-vitamin D level with standardized assays. There is a high prevalence of vitamin D insufficiency (25(OH)D < 50 nmol/l (i.e., 20 ng/mL)) or deficiency (25(OH)D < 25 nmol/l (i.e., 10 ng/mL)) in patients with fragility fractures and especially in those with a hip fracture. The evidence on the effects of vitamin D deficiency and/or vitamin D supplementation on fracture healing and material osseointegration is still limited. However, it appears that vitamin D have a rather positive influence on these processes. The fracture liaison service (FLS) model can help to inform orthopedic surgeons, all caregivers, and fractured patients about the importance of optimal vitamin D status in the management of patients with fragility fractures. Therefore, vitamin D status should be included in Capture the Fracture (R) program as an outcome of FLS in addition to dual-energy X-ray absorptiometry (DXA) and specific antiosteoporosis medication. Vitamin D plays a significant role in the pathophysiology and healing of fragility fractures and in rehabilitation after fracture. Correction of vitamin D deficiency should be one of the main outcomes in fracture liaison services.

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