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أمــل بنت محمد بن عبدالعزيز المحيميد

Associate Professor

استاذ مشارك- مساعدة وكيلة كلية العلوم للدراسات العليا والبحث العلمي

كلية العلوم
مبنى 5- الدور الثالث- مكتب رقم 185
المنشورات
مقال فى مجلة
2014

Spectrofluorimetric analysis of gemifloxacin mesylate in pharmaceutical formulations

, Amal M. Al-Mohaimeed*, Salma A. Al-Tamimi, . 2014

ورقة بحثيه

: A simple, rapid and highly sensitive spectrofluorimetric method was developed for determination of gemifloxacin mesylate (GFX) in tablets. The method is based on measuring the native fluorescence of GFX in isopropanol at 400nm after excitation at 272nm. The fluorescence–concentration plot was rectilinear over the range of 0.01–0.50mg/mL with a lower detection limitof1.19ng/mL andquantification limitof3.6ng/mL.The methodwasfully validatedand successfully appliedtothedetermination of GFX tablets with an average percentage recovery of 99.650.532. The method was extended to the stability study of GFX. The drug was exposed to acidic, alkaline, oxidative and photolytic degradation according to International Conference on Harmonizationguidelines.TherateofGFXdegradationwasfoundatitshighestinacidicconditions,andinitslowestintheneutral one. However, it was stable under dry heat and photolytic
 

نوع عمل المنشور
دكتوراه
رقم المجلد
29
رقم الانشاء
29
مجلة/صحيفة
Luminescence
الصفحات
127-131
مزيد من المنشورات
publications
بواسطة 1. Mahmood, Mudasir; Iqbal, Shahid; Jamshaid, Muhammad; Kalsoom, Ambreen; Amal M. Al-Mohaimeed; Iqbal, Rashid; Bibi, Firdous; Raza, Qasim; Elshikh, Mohamed Soliman
2024
publications
بواسطة Abdulhadi Hamad Al-Marri, Fatma Janene, Ali Moulahi, Amal T. Mogharbel, Eida S. Al-Farraj, Amal M. Al-Mohaimeed & Issam Mjejri
2023