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منال بنت محمد ابراهيم الخليفي --Manal Mohammed al khulaifi

Associate Professor

, ِ Associate professor, Microbiology, Department: botany & microbiology. King Saud UniversitAs

كلية العلوم
Building: 5- 3rd floor, Office: 326
المنشورات
مقال فى مجلة
2020

Characterization and biological investigation of silver nanoparticles biosynthesized from Galaxaura rugosa against multidrug-resistant bacteria

ABSTRACTBacterial drug resistance poses a global challenge to established antibacterial preventionand treatment schemes. Recent approaches focus on raising algal extracts’ efficacy by fusingthem to other antibacterial agents employing nanotechnology. Here, we successfully biosyn-thesized AgNPs using Galaxaura rugosa crude methanol extract (AgNPCR) and raw powderaqueous (AgNPAQ) solution. The resultant AgNPs were characterized using UV-visible spec-troscopy, Fourier-transform infrared spectroscopy, dynamic light scattering, and transmissionelectron microscopy. The AgNPs were spherical and ranged between 60 to 114.4 nm. Thepresence of the hydroxyl group and alkenes propped AgNPs biosynthesis. We investigatedAgNPs antibacterial and antibiofilm activity against eighteen medically important bacteria,including multidrug-resistant bacteria. The sensitive and resistant Acinetobacter baumannii andStaphylococcus aureus were the most affected strains. The biofilm of MDR strains was mostlydisturbed, indicating the reduced bacterial fitness in resistant strains. These results may aidantibacterial agents’ development by investing in natural resources available abundantly in ourenvironment.

نوع عمل المنشور
Article
اسم الناشر
Taylor and Francis online
رقم المجلد
14
مجلة/صحيفة
Journal of Taibah University for Science
الصفحات
1651-1659
مزيد من المنشورات
publications

Abstract

بواسطة Reem E. Alarfaj 1,2, Manal M. Alkhulaifi 1 , Ahmed J. Al-Fahad 3 , Shokran Aljihani 4 , Alaa Eldeen B. Yassin 5 , Majed F. Alghoribi 2,* and Majed A. Halwani
2022
تم النشر فى:
MDPI
publications

ABSTRACTBacterial drug resistance poses a global challenge to established antibacterial preventionand treatment schemes. Recent approaches focus on raising algal extracts’ efficacy by fusingthem…

بواسطة Raghad R. Alzahrani , Manal M. Alkhulaifi , Nouf M. Alenazi , Nawal M. Almusayeib , Musarat Amina , Manal A. Awad , Aarif H. Elmubarak & Noura S. Aldosari
2020
تم النشر فى:
Taylor and Francis online
publications

Abstract

بواسطة Mashael R. Aljumaah1 , Manal M. Alkhulaifi1 , Alaeldein M. Abudabos2 , Abdulaziz Alabdullatifb2 , Aarif H. El-Mubarak3,4, Ali R. Al Suliman5 , Dragana Stanley
2020