المناصب الإداريـــة

التعين على وظيفة معيد بقسم النبات والأحياء الدقيقة (1413هـ)

التعيين على رتبة أستاذ مساعد بقسم النبات والأحياء الدقيقة (1423هـ)

التعيين على رتبة أستاذ مشارك بقسم النبات والأحياء الدقيقة (1431هـ)

التعيين على رتبة أستاذ بقسم النبات والأحياء الدقيقة (1436هـ)y

المناصب الإداريـــة

المشرف على كرسي أبحاث فيروس كوفيد-19 – جامعة الملك سعود (23/5/1443هـ حتى الآن).

 مدير مركز التميز في التقنية الحيوية – جامعة الملك سعود (2/11/1441هـ- 1/11/1443هـ (

  رئيس قسم النبات والأحياء الدقيقة – كلية العلوم – جامعة الملك سعود (13/10/1437هـ الى 12/10/1441هـ).

نائب مدير مركز التميز في التقنية الحيوية – جامعة الملك سعود (2009-2012)

 مدير برنامج مراكز التميز البحثي - جامعة الملك سعود (2007-2013)

المشرف الرئيسي للمختبر المركزي للأبحاث بقسم النبات والأحياء الدقيقة – كلية العلوم – جامعة الملك سعود.

مستشار في وكالة الجامعة للتبادل المعرفي ونقل التقنية – جامعة الملك سعود.

رئيس اللجنة الفرعية للكليات العلمية لأخلاقيات البحوث على الكائنات الحية.

ممثل وزارة التربية والتعليم في اللجنة الوطنية لأخلاقيات البحث العلمي (2018).

 عضو مبادرة التقنية الحيوية، كلية العلوم، جامعة الملك سعود (2002).

 عضو لجنة المركز الوطني للقياس في التعليم العالي (2014).

عضو مبادرة التكنولوجيا الحيوية، كلية العلوم (2002).

عضوية المجالس واللجـــان

• عضو مجلس إدارة مركز التميز في التقنية الحيوية – جامعة الملك سعود (2007- حتي الأن)
• عضو اللجنة الدائمة لأخلاقيات البحوث بجامعة الملك سعود ( 1440هـ الى الآن).
• عضو لجنة النظر في مخالفات أحكام نظام أخلاقيات البحث العلمي على المخلوقات الحية بمدينة الملك عبد العزيز للعلوم والتقنية (1440هـ الى الآن).
• مستسار وعضو لعدد من اللجان بالمركز الوطني للقياس والتقويم في لجنة التعليم العالي (2012 – حتي الآن)
• عضو لجنة تحكيم جائزة الملك فيصل العالمية ـــ فرع علوم الحياة (2020م)
• ممثل وزارة التعليم في اللجنة الوطنية للأخلاقيات الحيوية بمدينة الملك عبد العزيز للعلوم والتقنية 12/3/1439هـ الى 12/3/1442هـ.
• أمين مجلس قسم النبات والأحياء الدقيقة (2002-2005)
• عضو في لجنة المعادلات والجداول الدراسية في قسم النبات والأحياء الدقيقة للعام الجامعي 1423/1424هـ
• ممثل قسم النبات والأحياء الدقيقة وعضو لجنة كلية العلوم بمعهد الأمير عبد الله للبحوث والدراسات الاستشارية.
• ممثل قسم النبات والأحياء الدقيقة وعضو لجنة الكلية لبرنامج الماجستير في الأحياء الجزيئية والهندسة الوراثية.
• عضو اللجنة العلمية للمؤتمر السعودي الثالث للعلوم، كلية العلوم /جامعة الملك سعود/ 20 إلى 23 - 2- 1428هـ الموافق 10 إلى 13 - 3- 2007م.
• الانضمام للهيئة الوطنية للتقويم والاعتماد الأكاديمي (NCAAA) خلال السنوات الماضية  كعضو في لجنة مراجعين مع الهيئة الوطنية لبرنامج الاعتماد والتقييم الأكاديمي لاعتماد برامج الدراسات العليا بجامعة الملك عبد العزيز (جدة) في العام 2022، وجامعة الملك خالد (أبها) في اعتماد برنامج الماجستير  عام 2021، وبرنامج الدراسات العليا بجامعة الطائف عام 2020.

عضوية الجمعيات العلمية

• عضو الجمعية الأسترالية للاحياء الدقيقة  -أستراليا (2014 حتي الأن).
• عضو الجمعية السعودية للتقنية الحيوية (2008 م حتى الان(.
• عضو الجمعية السعودية للاحياء الدقيقة الطبية والامراض المعدية )2008 م حتى الان(.
• عضو الجمعية السعودية لعلوم الحياة  (2009 م حتي الان) هـ حتى الان.
• عضو الجمعية العلمية الامريكية للاحياء الدقيقة  -الولايات المتحدة الامريكية (1997-1998).

المقررات التي قمت بتدريسها

1. 250 حدق علم الفيروسات
2. 450 حدق فيروسات ممرضة
3. 451 حدق علم المناعة
4. 499 حدق مشروع بحث
5.  511 حدق علم الفيروسات المتقدم
6. 611 حدق الأحياء الجزئية للفيروسيات
7. 612 حدق التقنيات والتطورات في دراسة الفيروسات

المشاريع البحثية

1. Epidemiological characteristics and genetic factors affecting the circulation and evolution of respiratory viruses in Saudi Arabia (2015-Present). ONGOING
2. Influenza Virus Evolution (2014). Completed
3. Development of Respiratory Viral Particulate Subunit Vaccine (2011). Completed
4. DNA vaccination of cervical cancer patients with rearranged oncogenes of the human pappillomavirus type 16 (2008-2011).  Completed
5. Development and validation of molecular diagnostic kit using nano- and recombinant DNA technology for: A- Mutation detection and B- Interferon monitoring (2008-2011). Completed
6. Using Nano-technology Techniques for Fabrication of 3D Biodegradable Scaffolds for Tissue Engineering (2008-2015) Completed.
7. Molecular Genetic Bio-Markers Associated with the Development of Viral Hepatitis in Saudi Patients (2009-2012). Completed
8. Multiplex PCR for detection Respiratory Viruses in young children in Riyadh (2005-2008). Completed

RECENT PUBLICATIONS (⇒ All Publications )

1. Akram A. Alfuraydi, Ibrahim M. Aziz, Fahad N. Almajhdi. Assessment of antioxidant, anticancer, and antibacterial activities of the rhizome of ginger (Zingiber officinale). Journal of King Saud University - Science 36 (2024) 103112.

2. Saeed U, Piracha ZZ, Alrokayan S, Hussain T, Almajhdi FN, Waheed Y. Immunoinformatics and Evaluation of Peptide Vaccines Derived from Global Hepatitis B Viral HBx and HBc Proteins Critical for Covalently Closed Circular DNA Integrity. Microorganisms. 2023 Nov 21;11(12):2826. doi: 10.3390/microorganisms11122826. PMID: 38137971; PMCID: PMC10745757.

3. Khalid HF, Bibi S, Ali A, Fawad N, Shams MU, Idrees W, Waqas M, Rafique S, Khan A, Khan F, Almajhdi FN. Decoding the mystery of MMTV-like virus and its relationship with breast cancer metastasis. J Infect Public Health. 2023 Sep;16(9):1396-1402. doi: 10.1016/j.jiph.2023.07.004. Epub 2023 Jul 14. PMID: 37480670.

4. Naushad SM, Mandadapu G, Ramaiah MJ, Almajhdi FN, Hussain T. The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants. Sci Rep. 2023 Aug 11;13(1):13078. doi: 10.1038/s41598-023-40114-8. PMID: 37567916; PMCID: PMC10421879.

5. Islam A, Deeba F, Tarai B, Gupta E, Naqvi IH, Abdullah M, Dohare R, Ahmed A, Almajhdi FN, Hussain T, Parveen S. Global and local evolutionary dynamics of Dengue virus serotypes 1, 3, and 4. Epidemiol Infect. 2023 Jun 9;151:e127. doi: 10.1017/S0950268823000924. PMID: 37293986; PMCID: PMC10540175.

6. Alkubaisi NA, Aziz IM, Alsaleh AN, Alhetheel AF, Almajhdi FN. Molecular Profiling of Inflammatory Mediators in Human Respiratory Syncytial Virus and Human Bocavirus Infection. Genes (Basel). 2023 May 17;14(5):1101. doi: 10.3390/genes14051101. PMID: 37239461; PMCID: PMC10218554.

7. Dudin GA, Aziz IM, Alzayed RM, Ahmed A, Hussain T, Somily AM, Alsaadi MM, Almajhdi FN. Genetic Diversity and Evolutionary Kinetics of Influenza A Virus H3N2 Subtypes Circulating in Riyadh, Saudi Arabia. Vaccines (Basel). 2023 Mar 20;11(3):702. doi: 10.3390/vaccines11030702. PMID: 36992286; PMCID: PMC10054866.

8. Waqas M, Aziz S, Liò P, Khan Y, Ali A, Iqbal A, Khan F, Almajhdi FN. Immunoinformatics design of multivalent epitope vaccine against monkeypox virus and its variants using membrane-bound, enveloped, and extracellular proteins as targets. Front Immunol. 2023 Jan 26; 14:1091941. doi: 10.3389/fimmu.2023.1091941. PMID: 36776835; PMCID: PMC9908764.

9. Alsaleh AN, Aziz IM, Alkubaisi NA, Almajhdi FN. Genetic analysis of human parainfluenza type 2 virus in Riyadh, Saudi Arabia. Virus Genes. 2023 Oct 31. doi: 10.1007/s11262-023-02035-6. Epub ahead of print. PMID: 37906378.

10. Muhammad Hanifa, Muhammad Salman, Muqaddas Fatima, Naila Mukhtar, Fahad N. Almajhdi, Nasib Zaman, Muhammad Suleman, Syed Shujait Ali, Yasir Waheed and Abbas Khan Mutational analysis of the spike protein of SARS-COV-2 isolates revealed atomistic features responsible for higher binding and infectivity. Frontiers in Cell and Developmental Biology; 17 January 2023 https://doi.org/10.3389/fcell.2022.940863

11. Alzayed RM, Aziz IM, Alsaleh AN, Dudin GA, Ahmed AA, Hussain T, Alshememry AK, Somily AM, Alsaadi MM, Almajhdi FN. ON-1 and BA-IX Are the Dominant Sub-Genotypes of Human Orthopneumovirus A&B in Riyadh, Saudi Arabia. Genes (Basel). 2022 Dec 5;13(12):2288. doi: 10.3390/genes13122288. PMID: 36553555; PMCID: PMC9778264.

12. Alamri KA, Farrag MA, Aziz IM, Dudin GA, Mohammed AA, Almajhdi FN. Prevalence of Human Coronaviruses in Children and Phylogenetic Analysis of HCoV-OC43 during 2016-2022 in Riyadh, Saudi Arabia. Viruses. 2022 Nov 22;14(12):2592. doi: 10.3390/v14122592. PMID: 36560596; PMCID: PMC9784458.

13. Aziz S, Almajhdi FN, Waqas M, Ullah I, Salim MA, Khan NA, Ali A. Contriving multi-epitope vaccine ensemble for monkeypox disease using an immunoinformatics approach. Front Immunol. 2022 Oct 13;13:1004804. doi: 10.3389/fimmu.2022.1004804. PMID: 36311762; PMCID: PMC9606759.

14. Aziz IM, Farrag MA, Bhat R, Ahmed A, Alkubaisi NA, Alzayed RM, Dudin GA, Almajhdi FN. Development and Validation of Rapid In-House Diagnostic ELISA Kits for Detection of Human Orthopneumovirus in Clinical Samples. Diagnostics (Basel). 2022 Apr 6;12(4):912. doi: 10.3390/diagnostics12040912. PMID: 35453960; PMCID: PMC9029150.

15. Dar HA, Almajhdi FN, Aziz S, Waheed Y. Immunoinformatics-Aided Analysis of RSV Fusion and Attachment Glycoproteins to Design a Potent Multi-Epitope Vaccine. Vaccines (Basel). 2022 Aug 24;10(9):1381. doi: 10.3390/vaccines10091381. PMID: 36146460; PMCID: PMC9502547.

16. Shafat Z, Ahmed MM, Almajhdi FN, Hussain T, Parveen S, Ahmed A. Identification of the Key miRNAs and Genes Associated with the Regulation of Non-Small Cell Lung Cancer: A Network-Based Approach. Genes (Basel). 2022 Jun 29;13(7):1174. doi: 10.3390/genes13071174. PMID: 35885958; PMCID: PMC9317345.

17. Abu Hamza, Abdus Samad, Zahoor Ahmad Parray , Sajda Ara , Anwar Ahmed , Fahad N Almajhdi, Tajamul Hussain, Asimul Islam, Shama Parveen. Mutation in the CX3C Motif of G Protein Disrupts Its Interaction with Heparan Sulfate: A Calorimetric, Spectroscopic, and Molecular Docking Study. International Journal of Molecular Science,2022 Feb 9;23(4):1950. doi: 10.3390/ijms23041950

18. Taimoor Khan, Muhammad Abdullah, Tayyba Fatima Toor, Fahad N Almajhdi, Muhammad Suleman, Arshad Iqbal, Liaqat Ali, Abbas Khan, Yasir Waheed, Dong-Qing Wei. Evaluation of the Whole Proteome of Achromobacter xylosoxidans to Identify Vaccine Targets for mRNA and Peptides-Based Vaccine Designing Against the Emerging Respiratory and Lung Cancer-Causing Bacteria. Frontiers in Medicine (Lausanne) 2022 Feb 4; 8:825876.doi: 10.3389/fmed.2021.825876

19. Zubia Jamil, Fahad N Almajhdi, Samreen Khalid, Muhammad Asghar Jamal Ahmed, Yasir Waheed. Comparison of Low-Versus High-Dose Steroids in the Clinical Outcome of Hospitalized COVID-19 Patients. Antibiotics (Basel). 2021 Dec 9;10(12):1510. doi: 10.3390/antibiotics10121510

20. Abu Hamza, Abdus Samad, Md Ali Imam, Md Imam Faizan, Anwar Ahmed, Fahad N Almajhdi, Tajamul Hussain, Asimul Islam, Shama Parveen. Structural Characterization of Ectodomain G Protein of Respiratory Syncytial Virus and Its Interaction with Heparan Sulfate: Multi-Spectroscopic and In Silico Studies Elucidating Host-Pathogen Interactions. Molecules. 2021 Dec 6;26(23):7398. doi: 10.3390/molecules26237398.

21. Syed, A Al-Shwaiman, HA Al Khulaifi, MM, Al Zahrani, RR Almajhdi, FN Elgorban, AM. Integrating plasmonic effect and nano-heterojunction formation for boosted light harvesting and photocatalytic performance using CaWO4/Ag2MoO4 and its antibacterial applications. Materials Science in Semiconductor Processing. DOI10.1016/j.mssp.2021.105921. OCT 2021

22. Parray, ZA Ahmad, F Hassan, MI Ahmed, A Almajhdi, FN Malik, A Hussain, T Islam, A Structural Refolding and Thermal Stability of Myoglobin in the Presence of Mixture of Crowders: Importance of Various Interactions for Protein Stabilization in Crowded Conditions. Molecules DOI10.3390/molecules26092807. MAY 2021

23. Ayman Mubarak, Bahauddeen Alrfaei, Abdullah Aljurayyan, Mahfoudh M Alqafil, Mohamed A Farrag, Maaweya E Hamed, Bandar Alosaimi, Fahad Almajhdi. Wael Alturaiki.In vivo and in vitro Evaluation of Cytokine Expression Profiles During Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection. Journal of Inflammation Research. 2021.

24. Farrag, Mohamed A; Amer, Haitham M; Bhat, Rauf; Almajhdi, Fahad N. Sequence and phylogentic analysis of MERS-CoV in Saudi Arabia, 2012-2019. Virology journal. DOI:10.1186/s12985-021-01563-7. 2021

25. Bhat, R; Almajhdi, FN. Induction of Immune Responses and Immune Evasion by Human Bocavirus. International Archives of Allergy and Immunology. DOI: 10.1159/000514688. 2021

26. Naushad, Shaik Mohammad; Alrokayan, Salman A; Almajhdi, Fahad N; Hussain, Tajamul. Influence of RFC1 c.80A>G Polymorphism on Methotrexate-Mediated Toxicity and Therapeutic Efficacy in Rheumatoid Arthritis: A Meta-analysis. The Annals of pharmacotherapy. DOI:10.1177/10600280211002053. 2021

27. Abu Hamza, Zoya Shafat, Zahoor Ahmad Parray, Malik Hisamuddin, Wajihul Hasan Khan, Anwar Ahmed, Fahad N. Almajhdi, Mohamed A. Farrag, Arif Ahmed Mohammed, Asimul Islam, and Shama Parveen.  Structural Characterization and Binding Studies of the Ectodomain G Protein of Respiratory Syncytial Virus Reveal the Crucial Role of pH with Possible Implications in Host-Pathogen Interactions. Acs Omega https://doi.org/10.1021/acsomega.1c00800. 2021

28. Alotaibi HJ, Almajhdi FN, Alsaleh AN, Obeid DA, Khayat HH, Al-Muammer TA, Tulbah AM, Alfageeh MB, Al-Ahdal MN, Alhamlan FS. Association of sexually   transmitted infections and human papillomavirus co-infection with abnormal cervical cytology among women in Saudi Arabia. Saudi Journal of Biological Sciences. https://doi.org/10.1016/j.sjbs.2020.03.021

29. Rauf Bhat R, Farrag MA, Almajhdi FN. Double-edged role of natural killer cells during RSV infection. International Reviews of Immunology, DOI: 10.1080/08830185. 2020.1770748

30. Aljowaie RM, Almajhdi FN, Ali HH, El-Wetidy MS, Shier MK. Inhibition of hepatitis C virus genotype 4 replication using siRNA targeted to the viral core region and the CD81 cellular receptor. Cell Stress Chaperones. 2020;25(2):345-355. doi:10.1007/s12192-020-01077-1

31. Farrag MA, Amer HM, Aziz IM, Alsaleh AN, Almajhdi FN. The emergence of sub genotype ON-1 of Human orthopneumovirus type A in Riyadh, Saudi Arabia: A new episode of the virus epidemiological dynamic. J Med Virol. 2020;92(8):1133-1140. doi:10.1002/jmv.25643.

CONFERENCES AND ABSTRACTS

1. Ninth Annual ImVacS. The immunotherapies and Vaccine Summit, August 11-14, 2014, Boston, MA, USA.

2. OMICS Group 5th World Congress on Biotechnology, June 25-27, 2014, Valencia, SPAIN. A cross-sectional surveillance study for respiratory viruses in hospitalized children at Riyadh, Saudi Arabia (Almajhdi FN, Amer HM).

3. 12th Asia-Pacific Bioinformatics Conference, January 17-19, 2014, Shanghai, CHINA. Group B Strains of Human Respiratory Syncytial Virus in Saudi Arabia: Molecular and Phylogenetic Analysis (Almajhdi FN, Farrag MA, Amer HM).

4. International Conference on Environmental, Biological and Ecological Sciences, and Engineering, March 14-15, 2013, Rio de Janeiro, BRAZIL. Epidemiology and Molecular Characteristics of the Principal Respiratory Viruses Circulating Among Saudi Population (Almajhdi FN, Amer HM).

5. Australian Society for Microbiology Annual Scientific meeting 2013, July 7-10, 2013,              Adelaide, AUSTRALIA. Human Respiratory Viruses in Saudi Arabia: Epidemiological, Molecular and Phylogenetic Analysis (Almajhdi FN, Amer HM).
6. 4th International Conference of Virology, November 14-16, 2012, Sharm El Sheikh,                EGYPT. Cell-based Screening of Cytotoxic and Antiviral Activities of Selected Medicinal Plants from Saudi Arabia, (Latif A, Amer HM, Almajhdi FN).
7. 27th International Papillomavirus Conference and Clinical Workshop, September  17-22, 2011, Berlin, GERMANY.
8. The 2nd International Conference on Bioinformatics and Biomedical Technology  (ICBBT 2010), April 17-20, 2010, Chengdu, CHINA.
9. 26th International Papillomavirus Conference, July 4-9, 2010, Montreal, CANADA
10. International meeting of "Human Virology", 2003, Baltimore, USA.
11.  Proceedings of the VIIIth International Symposium on Nidoviruses, 2000, Split  Rock, Pennsylvania, USA. Interactions of cellular proteins with the positive strand of  3' untranslated RNA and the nucleoprotein gene of porcine reproductive and  respiratory syndrome virus (Majhdi FN, Kapil S).
12. Proceedings of the VIIIth international symposium on Nidoviruses, 2000, Split Rock, Pennsylvania, USA. Production, characterization and use of monoclonal antibodies against porcine reproductive and respiratory syndrome virus 3' untranslated region and nucleoprotein RNA binding proteins (Shanmukhappa K,Majhdi FN, Kapil S).
13.  American Society for Virology – Annual Meeting, 1999, University of Massachusetts,            Amherst, Massachusetts, USA. Interactions of cellular proteins with the positive  strand of 3'-untranslated region RNA and the nucleoprotein gene of porcine  reproductive and respiratory syndrome virus (Majhdi FN, Kapil S).
14.  79th Annual Meeting, Conference of Research Workers in Animal Diseases, 1998,  Chicago, IL, USA. Development, characterization, and diagnostic applications of  monoclonal antibodies against porcine reproductive and respiratory syndrome virus  and bovine rotavirus, (Al-Majhdi F, Al-Yousif Y, Birney J, Chard-Bergstrom C, and  Kapil, S).
15.  Conference of Research Workers in Animal Diseases, 1997, Chicago, IL, USA.
16.  Characterization of a coronavirus from elk calves with diarrhea (Majhdi F, Minocha  HC, Kapil, S).
17.  Conference of Research Workers in Animal Diseases - 224, 1996, Chicago, IL, USA.  Molecular characteristics of an elk coronavirus (Fahad A, Minocha HC, Kapil S).
18. Conference of Research Workers in Animal Diseases - 77, 1996, Chicago, IL, USA.    Typing of bovine coronavirus isolates on the basis of relative susceptibility to  Hygromycin B (Fahad A, Minocha HC, Kapil, S).

براءات الإختراع

GENEBANK

MERS Coronavirus [16]

ORF1ab gene: KT624236, KT624237, KT624238, KT624239

S gene: KT624240, KT624241, KT624242, KT624243   

ORF3 gene: KT624244, KT624245, KT624246, KT624247   

ORF4b gene: KT624248, KT624249, KT624250, KT624251

Influenza B viruses [14]

HA gene: JQ771075, JQ771077, JQ771079, JN663826, KC709818

NA gene: JQ771076, JQ771078, JN663827, KC709817, KC709819

NS-2 gene: GU135839

Polymerase genes: KC709814, KC709814, KC709816

Respiratory syncytial viruses [27]

G gene: JF714705, JF714706, JF714707, JF714708, JX131637, JX131638, JX131639, JX131640, JX131641, JX131642, JX131643, JX131644, JX131645, KC791694, KC791695, KC791696, KC791697, KC763335, KC763337, KC763339     F gene: JF714709, JF714710, JF714711, JF714712, KC763334, KC763336, KC763338

Parainfluenza viruses [7]

HPIV-3 (HN): HM460886, HM460887, JX131646, JX131647, JX131648, JX131649

HPIV-2 (HN): HM460888

Hepatitis B virus [42]

X-gene: KF018196, KF018197, KF018198, KF018199, KF018200, KF018201, KF018202, KF018203, KF018204, KF018205, KF018206, KF018207, KF018208, KF018209, KF018210, KF018211, KF018212

Core/pre-core gene: KF018176, KF018177, KF018178, KF018179, KF018180, KF018181, KF018182, KF018183, KF018184, KF018185, KF018186, KF018187, KF018188, KF018189, KF018190, KF018191, KF018192, KF018193, KF018194, KF018195.

Surface gene: KF018213, KF018214, KF018215, KF018216, KF018217.

Human Metapneumovirus [25]

F gene: KT032157, KT032158, KT032159, KT032160, KT032161, KT032162, KT032163, KT032164, KT032165, KT032166, KT032167, KT032168, KT032169, KT032170, KT032171, KT032172 G gene: KT032173, KT032174, KT032175, KT032176, KT032177, KT032178, KT032179, KT032180, KT032181.

SCIENTIFIC LINKS

Research Gate: https://www.researchgate.net/profile/Fahad_Almajhdi

ORCID Number: https://orcid.org/0000-0002-0135-7015

Google Scholar: https://scholar.google.com/citations?hl=en&user=OGZZWHcAAAAJ

Web of Science Researcher Id: AAM-4403-2020s