Preparation of Chito-Oligomers by Hydrolysis of Chitosan in the Presence of Zeolite as Adsorbent
Ibrahim, Khalid A. . 2016
Abstract: An increasing interest has recently been shown to use chitin/chitosan oligomers
(chito-oligomers) in medicine and food fields because they are not only water-soluble, nontoxic, and
biocompatible materials, but they also exhibit numerous biological properties, including antibacterial,
antifungal, and antitumor activities, as well as immuno-enhancing effects on animals. Conventional
depolymerization methods of chitosan to chito-oligomers are either chemical by acid-hydrolysis under
harsh conditions or by enzymatic degradation. In this work, hydrolysis of chitosan to chito-oligomers
has been achieved by applying adsorption-separation technique using diluted HCl in the presence
of different types of zeolite as adsorbents. The chito-oligomers were retrieved from adsorbents and
characterized by differential scanning calorimetry (DSC), liquid chromatography/mass spectroscopy
(LC/MS), and ninhydrin test.
Abstract: An increasing interest has recently been shown to use chitin/chitosan oligomers
(chito-oligomers) in medicine and food fields because they are not only water-soluble, nontoxic, and…