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Dr. Faizah Binjubair

Assistant Professor

Assistance Professor

كلية الصيدلة
Building (8), Second floor, Office number (75)
المنشورات
مقال فى مجلة
2010

Anti-Tubercular Activity of Isatin Derivatives

Bin-Jubair, Fayzah A. S. . 2010

 

Tuberculosis (TB) remains among the world’s great public health challenges. Worldwide resurgence of TB is due to two major problems: the acquired immunodeficiency syndrome (AIDS) epidemic, which started in the mid-1980s, and the outbreak of multidrug resistant tuberculosis (MDR-TB). Thus, there is an urgent need for anti-TB drugs with improved properties such as: Enhanced activity against MDR strains, reduced toxicity, shortened duration of therapy, rapid mycobactericidal mechanism of action and the ability to penetrate host cells and exert antimyco-bacterial effects in the intracellular environment. Indoline-2,3-dione (isatin) derivatives are reported to show anti-tubercular activities, accordingly, isatin is a versatile lead molecule for designing of potential anti-tubercular agent. The current review outlines isatin derivatives with potential anti-tubercular activity.

نوع عمل المنشور
ماجستير
مزيد من المنشورات
publications

The present invention relates to an isatin derivative having the formula (I), 
a medicament for treatment of tuberculoses containing that isatin derivative as Well as a method for preparing…

بواسطة Fayzah bint Ahmad S.Bin Jubair,, Tarek Aboul-Fadl Mohamed Hassan,
2013
publications

Tuberculosis (TB) remains among the world’s great public health challenges.Worldwide resurgence of TB

is due to two major problems: the AIDS epidemic, which started in the mid-1980s, and…

بواسطة Fayzah A.S. Bin-Jubair, Tarek Aboul-Fadl, Omima Aboul-Wafa
2010
publications

 

بواسطة Fayzah A. S. Bin-Jubair, Tarek Aboul-Fadl
2010