Application of a mesoporous structure as an efficient catalyst for the rapid and green synthesis of uracil derivatives in a recyclable environment
This study describes a benign, rapid, and highly efficient practical approach for synthesizing bis(6-amino-1,3-dimethyluracil-5-yl) methanes using 1,4-bis(pyridin-1-ium)benzene trifluoroacetate coordinated to chloropropyl functionalized SiO2-nano-NiFe2O4 (BPTCSBF) as a bi-functional and reusable mesoporous catalyst in a recyclable green media. The catalytic scope of bi-functional BPTCSBF with acidic (similar to NH+) and basic (CF3COO-) sites was very broad and useful, as it rapidly produced products (1a-15a) from the reaction of various aryl-aldehydes with 6-amino-1,3-dimethyluracil in excellent yields (90-98%, 7-17 min) under optimal conditions (0.01 g catalyst, 60 degrees C, 1 mL EtOH:H2O). This generality and high functionality were backed by the presentation of a rational mechanism. Easy magnetic separation of the catalyst with an external magnet, suitable one-pot procedure, high reproducibility of the catalyst with brilliant performance up to eight cycles, mild temperature, easy work-up, and synthesis/characterization of new derivatives to the literature are other highlights of the current work.
The development of advanced electrode materials with superior electrochemical performance is imperative to meet the growing demands of modern energy storage technologies.…
This study describes a benign, rapid, and highly efficient practical approach for synthesizing bis(6-amino-1,3-dimethyluracil-5-yl) methanes using 1,4-bis(pyridin-1-ium)…
The mounting global imperative for sustainable energy storage and effective wastewater treatment necessitates the innovation of multifunctional materials capable of…