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أ.د.علي سمير سعد

Professor

استاذ

كلية العلوم الطبية التطبيقية
المبنى 24 الدور 2 رقم مكتب 2275
المنشورات
مقال فى مجلة
2021

Chemotaxis Model for Drug Delivery Using Turing’s Instability and Non-Linear Diffusion

This paper is devoted to the study of the chemotaxis model for drug delivery purposes. The pattern formation for a volume-filling with nonlinear diffusive terms is investigated. The proposed mathematical model is governed by a reaction–diffusion system modeling the interaction between the cell density and the concentration of the chemoattractant. We investigate the pattern formation for the model using Turing’s principle and linear stability analysis. An asymptotic expansion is used to linearize the nonlinear diffusive terms. Next, we introduce an implicit finite volume scheme; it is presented on a triangular mesh satisfying the orthogonality condition. Finally, numerical results showing the formation of the spatial pattern for the chemotaxis model are presented and analyzed. The results demonstrate promising progress in understanding the process of controlling and designing targeted drug delivery.

نوع عمل المنشور
research project
اسم الناشر
mdpi
مدينة النشر
Switzerland
رقم المجلد
11
رقم الانشاء
11
الصفحات
11
مزيد من المنشورات
publications

In this paper, we are concerned with the convergence analysis of a combined finite volume-non-conforming finite element scheme, to approximate the two incompressible phase flow with dynamic…

2022
تم النشر فى:
Advances in Computational Mathematics
publications

The purpose of this paper was to detect and separate the cluster intensity provided by Iron oxide nanoparticles (IO-NPs), in the MRI images, to investigate the drug delivery effectiveness. IO-NPs…

بواسطة Mohammed Almijalli , Ali Saad , Khalid Alhussaini , Adham Aleid , Abdullatif Alwasel
2021
تم النشر فى:
mdpi
publications

This paper is devoted to the study of the chemotaxis model for drug delivery purposes. The pattern formation for a volume-filling with nonlinear diffusive terms is investigated.

بواسطة 1. Mohammed Almijalli, Moustafa Ibrahim, Ali Saad and Mazen Saad
2021
تم النشر فى:
mdpi