Evaluating the Adverse Events Associated with Three Doses of the COVID-19 Vaccination in Adults in theWestern Region of Saudi Arabia: A Cross-Sectional Study
The Kingdom of Saudi Arabia was one of the countries earliest affected by the coronavirus
2019 (COVID-19) pandemic and had taken precautions including compulsory COVID-19 vaccination.
Both the ChAdOx1 nCoV-19 vaccine (Oxford AstraZeneca) and the BNT162b2 vaccine (Pfizer) were
approved by the Saudi Ministry of Health, followed by mRNA-1273 (Moderna), all of which were
used for population-wide vaccination. This study aimed to assess the short-term side effects following
the COVID-19 vaccinations among participants who had received all three doses in the western
region of Saudi Arabia. An online survey was distributed to the participants who received either
BNT162b2, ChAdOx1 nCoV-19, or mRNA-1273 vaccines, and the type of side effects and their severity
were evaluated. Fatigue and headache, pain at the site of the injection and muscle pain were the most
common side effects in all three doses. However, the severity depending on the type of vaccination
was significant only for the first and second dose, but not the third dose. In contrast, there was a
higher percentage of participants who encountered severe side effects from the third dose compared
to the first and second. Nevertheless, the majority of participants described all three doses’ side
effects to be moderately severe. A future evaluation could be made to access the individual types
of vaccination and compare between the side effects of the BNT162b2, ChAdOx1 nCoV-19, and
mRNA-1273 vaccines specifically for the booster dose.
The Kingdom of Saudi Arabia was one of the countries earliest affected by the coronavirus
2019 (COVID-19) pandemic and had taken precautions including compulsory COVID-19 vaccination.
…
The Kingdom of Saudi Arabia was one of the countries earliest affected by the coronavirus
2019 (COVID-19) pandemic and had taken precautions including compulsory COVID-19 vaccination.
…