Novel synthesis of CNTs/Cu nanodots-arabic gum nano-hybrid composites induce cytotoxicity and apoptosis in human breast and lung cancer cell lines
This research introduces a new hybrid material for potential cancer treatment. It combines carbon nanotubes decorated with copper nanodots and Arabic gum through an electroless reduction deposition technique. The resulting nanocomposite was thoroughly characterized confirming the successful decoration of carbon nanotubes with copper nanodots ranging in size from 1.55 to 7.77 nm. The hybrid material exhibits a high zeta-potential of − 20.3 mV, indicating excellent stability due to surface charge. The nanocomposite demonstrated cytotoxicity against MCF-7 breast cancer cells and A549 lung cancer cells in a dose-dependent manner. Notably, MCF-7 cells showed higher sensitivity to the hybrid material with (IC50) of 30.8 μg/ml compared to A549 cells with an IC50 of 48.23 μg/ml. Furthermore, the hybrid induced apoptosis in treated cells, as confirmed by apoptotic-related markers. This novel hybrid material holds promising potential for cancer therapy due to its high stability, targeted cytotoxicity, and induce apoptosis in cancer cells.
There are still not many meaningful alternatives to converting too-nitrogenated water into ammonia. This is mostly because it requires highly active and long-lasting catalysts.
This study investigated the effects of lanthanum oxide nanoparticles (La2O3 NPs) on cognitive and motor functions in female mice. We used behavioral tests, biochemical analysis, and tissue…
This research introduces a new hybrid material for potential cancer treatment. It combines carbon nanotubes decorated with copper nanodots and Arabic gum through an electroless reduction…