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Md Ashrafuzzaman

Professor

Professor

كلية العلوم
Bldg 5, Office 2A65
publication
Journal Article
2022

Current trends in bio-waste mediated metal/metal oxide nanoparticles for drug delivery

Nanoparticles have received much attention in biomedical applications due to their unique physicochemical properties. The metal/metal oxide nanoparticles are involved in various applications, including drug delivery, therapy, and diagnosis. Subsequently, many hazardous chemicals and organic solvents were utilized to synthesize the metallic nanoparticles. Therefore, the green synthesis came into the limelight to overcome the economic and environmental burden. The green synthesis represents the production of nanoparticles that reduce or terminate the use of hazardous materials and solvents that encourages environmental safety. The frequently utilized green materials in numerous metallic nanoparticle syntheses include microbes, plants, fruits, and other food sources. However, the burden on global food security and limited natural resources creates distress over environmental sustainability. Thus, adopting bio-waste materials to produce highly efficient, biocompatible, economic, and eco-friendly metallic nanoparticles could support waste valorization and lead to environmental sustainability. Therefore, the present review focuses on the various bio-waste materials adopted to synthesize metal/metal oxide nanoparticles. We have thoroughly discussed the potential of chemicals-mediated metal/metal oxide nanoparticles in different drug delivery applications such as tumor targeting, brain targeting, stimuli-responsive drug release followed by large molecules delivery. Consequently, this can open a new road for researchers to explore drug delivery applications using bio-waste mediated green synthesized metallic nanoparticles. Finally, the cytotoxicity aspects of such nanoparticles are meticulously discussed compared to chemically synthesized counterparts.

Publication Work Type
Drug delivery
Publisher Name
Journal of Drug Delivery Science and Technology
more of publication
publications
by Mohammad Ashrafuzzaman, R. E. Koeppe II, O. S. Andersen
2024
Published in:
Int. J. Mol. Sci.
publications

See the website …

by Mohammad Ashrafuzzaman
2023
Published in:
Taylor&Francis Group-CRC Press
publications

Nanoparticles have received much attention in biomedical applications due to their unique physicochemical properties. The metal/metal oxide nanoparticles are involved in various applications,…

by Jaswanth Gowda et al.
2022
Published in:
Journal of Drug Delivery Science and Technology