publication
Patent
2021
Energy-based method for drug design (US patent)
A method of designing aptamers includes building an aptamer by a seed-and-grow method optimizing screened coulomb interactions (SCI) and selecting aptamer length based on an aptamer target biological environment. Aptamers designed according to the method may comprise any DNA or RNA nucleotides. In particular (as example), aptamers may be designed according to the method to target lipids that may be found in membranes, such as liposomes or micelles. The lipids may be phosphatidylserine (PS) or phosphatidylcholine (PC).
Publication Work Type
Drug Discovery Method
Publisher Name
US patent
Volume Number
US10916330
Pages
1-23
more of publication
2024
Published in:
Int. J. Mol. Sci.
See the website …
2023
Published in:
Taylor&Francis Group-CRC Press
Nanoparticles have received much attention in biomedical applications due to their unique physicochemical properties. The metal/metal oxide nanoparticles are involved in various applications,…
2022
Published in:
Journal of Drug Delivery Science and Technology