Random urine albumin:creatinine ratio in high-risk pregnancy – is it clinically useful?
We evaluated the frequency of measurable albuminuria (P6.00 mg/L) for albumin:creatinine ratios (ACr) among 160 consecutive women attending high-risk clinics. Of last urine samples before delivery, 76 had measurable albuminuria and 41/76 (53.9%) had ACr P2 mg/mmol of which 7.3% had normal pregnancy outcome. 84 samples had albuminuria <6.00 mg/L and 43/84 (51.2%) had ACrP2 mg/mmol of which 25.6% had normal pregnancy outcome (p = 0.025). Excluding 48/160 (30.0%) dilute samples (urinary creatinine <3 mM), no samples with unmeasurable albuminuria had ACr P2 mg/mmol. In pregnancy, urine is often dilute and without measurable albuminuria, leading to a clinically relevant proportion of false positive results by ACr.
BACKGROUND: Routine surveillance of congenital anomalies has shown recent increases in ankyloglossia (tongue-tie) in British Columbia, Canada. We examined the temporal trends in ankyloglossia and…
OBJECTIVE: To describe temporal and regional variations in Canada in the use of operative vaginal delivery (OVD) at term for singleton pregnancies by pelvic station between 2004 and 2013.
OBJECTIVE: To identify the factors underlying the recent increase in maternal mortality ratios (maternal deaths per 100,000 live births) in the United States.