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Shaun Sabico

Assistant Professor

Assistant Professor and Deputy Director

كلية العلوم
Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, KSU
المنشورات
مقال فى مجلة
2023

The Metabolically Healthy Obese Phenotype: The Atypical Normal or Disorder in Progress?

The Metabolically Healthy Obese (MHO) is a unique phenotype of obesity in which individuals match the operational definition of obesity but do not display metabolic complications. Given this attribute, MHO has gained rapid interest in the field of adiposity research over the recent decades. Whether the MHO phenotype is apparently free of cardiometabolic abnormalities or simply a transient state of the metabolically unhealthy obese (MUO) remains controversial, but this ambiguous phenotype deserve clinical merit as it may serve as a missing conduit to further understand the complex nature of human obesity. Furthermore, shedding light in the still controversial MHO may help further research in in terms of customizing interventions aimed at decreasing the cardiometabolic risks associated with the MUO phenotypes and/or maintaining the “normalcy” of MHO over time. In this review, we aim to promote and update existing knowledge on the different metabolic health phenotypes of obesity as gathered from recent literature, primarily for the obese population and for primary care physicians who are first in-line in encountering these phenotypes. This may also help healthcare providers to have better awareness in identifying which obese phenotypes can actually benefit from weight loss programs. In light of available evidence, more longitudinal and translational studies are still needed to reach a universal definition of MHO.

اسم الناشر
Biolife Sas
رقم المجلد
37
رقم الانشاء
6
مجلة/صحيفة
Journal of Biological Regulators and Homeostatic Agents
الصفحات
2863-2876
مزيد من المنشورات
publications

This study investigated the differences and associations between serum levels of angiopoietin-like (ANGPTL)3, ANGPTL4, and ANGPTL8 in Saudi adolescents with varying levels of obesity and glycemia…

بواسطة Alenazi M, Sabico S, Alnaami AM, Wani K, Hussain SD, Al-Daghri NM
2024
تم النشر فى:
Elsevier
publications

Aim

This study evaluated the pesticide residues in some fruits collected from different markets in Saudi Arabia (SA) and determined potential health risks associated with them…

بواسطة Alokail MS, Elhalwagy MEA , Abd-Alrahman SH, Alnaami AM, Hussain SD, Amer OE, Sabico S, Al-Daghri NM
2024
تم النشر فى:
Elsevier
publications

Profoundly hearing-impaired individuals lack health-promotion education on healthy lifestyles, and this may be due to communication barriers and limited awareness of available resources. Therefore…

بواسطة Aljubair JM, Aldisi D, Bindayel IA, Aldhwayan MM, Sabico S, Alsaawi TA, Alghamdi E, Abulmeaty MA
2024
تم النشر فى:
MDPI