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Reem A. Alajmi

Associate Professor

Vice dean of science collage

كلية العلوم
Bulding 5, 3rd floor, office # 5T005
المنشورات
مقال فى مجلة
2022
تم النشر فى:

Effect of biosynthesized silver nanoparticles by Garcinia mangostana extract against human breast cancer cell line MCF-7

Breast cancer is the greatest common malignancy in females. This syndrome represents a serious public health problem that
needs additional study to define its prediction and specific treatment. MCF-7 is a usually used breast cancer cell line that has
been spread for many years by multiple groups. It shows to be a suitable model cell line for breast cancer studies worldwide,
including those concerning anticancer. Anticancer and anti-inflammatory influences are important to treat the threats of chronic
inflammation related with chronic diseases. Natural products have made and are remaining to make vital influences to the search
for new anticancer agents. The use of natural foodstuffs in relationship with green nanoparticles has drawn attention because
of its easy and eco-friendly protocol. Therefore, we aimed to investigate the antiproliferative activity of silver nanoparticles
biosynthesized by mangosteen peel extract (MPE) on human breast cancer cell line (MCF-7) using [3-(4, 5-dimethylthiazolyl)-2,
5-diphenyl-tetrazolium bromide (MTT) method. In the present study serial concentrations (5, 10, 15, 50, 70, µg/mL) of cells
biosynthesized silver nanoparticles by (MPE) was tested against MCF-7 cell lines showed a cytotoxic effects, morphological
degeneration, damaging and has more effectiveness against breast cancer cells. The results showed a substantial a high reducing
power, a sensible antiproliferative role and antioxidant activity. The results showed that silver nanoparticles biosynthesized by
mangosteen peel extract (MPE) can be regarded as a suitable candidate for designing anticancer pharmaceutical preparations

نوع عمل المنشور
project
مجلة/صحيفة
Food Science and Technology
الصفحات
online
مزيد من المنشورات
publications
بواسطة Afnan S. Al-Qurashi, Ashraf M. Mashaly, Reem Alajmi, Mohamed S. Al-Khalifa, Lamjed Mansour, Suliman Y. Al-Omar, Mostafa R. Sharaf, Abdulrahman S. Aldawood, Hathal M. Al-Dhafer, Tony Hunter, Masha’el Y. Almutawa, Ashraf M. Ahmed
2023
تم النشر فى:
Journal of Medical Entomology
publications
بواسطة Hend M Alharbi, Yasser A Elnakady, Badr A Aldahmash, Reem Alajmi, Zeid A ALOthman, Ahmed-Yacine Badjah-Hadj-Ahmed, Ahmad Aqel, Ashraf M Ahmed
2023
تم النشر فى:
Journal of Medical Entomology
publications

Aedes aegypti (Culicidae), the mosquito that causes yellow fever, is regarded as a significant vector for
many disease agents. The current study sought to learn more about mosquito mid-gut…

بواسطة Sumaiah Al-Ghamdi, Mohamed A. Farrag, Rewaida Abdel-Gaber, Albandary Alrajeh, Saeed El-Ashram, Ommer Dafalla, Guillermo Tellez-Isaias, Mohammed Alkuriji , Reem Alajmi.
2023