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Dr. Rais Ahmad Khan

Associate Professor

Associate Professor in Inorganic Chemistry

كلية العلوم
2A 89, Building 5, Department of Chemistry, College of Science, King Saud University, Riyadh

99567
krais
السيرة الذاتية

Dr. Rais Ahmad Khan

نص السيرة الذاتية

ACADEMIC PROFILE

Ph.D. Chemistry (2011)
Aligarh Muslim University, Aligarh, INDIA
Thesis Title: “PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES OF NEW METAL CHELATES”.
 
M.Sc. (Inorganic Chemistry) (2006)
Aligarh Muslim University, Aligarh, INDIA
Academic Grade: First Class
 
B.Sc. (Hons.) Chemistry (2004)
Aligarh Muslim University, Aligarh, INDIA
Academic Grade: First Class
 
TEACHING EXPERIENCE

 
Associate Professor (Inorganic Chemistry) (September 2019-till date) at Department of Chemistry, College of Science, King Saud University, Riyadh, KSA.
 
Assistant Professor (Inorganic Chemistry) (February 2012-September 2019) at Department of Chemistry, College of Science, King Saud University, Riyadh, KSA.

 
RESEARCH EXPERIENCE

  

  • Working in collaboration with Prof. Banglin Chen (Dean's Distinguished Chair Professor Microsoft President’s Endowed Professor) (March 2019 –till today).

 

  • Worked as Visiting Professor (26th June - 30th July 2019) in collaboration with Prof. Banglin Chen,
    Department of Chemistry, University of Texas at San Antonio, UNITED STATES OF AMERICA.

 

  • Worked in collaboration with Prof. Jan Reedijk (University of Leiden, THE NETHERLANDS) and Prof. Angela Casini (Cardiff University, Cardiff, United Kingdom) (2012-2015)

 

  • Worked as Visiting Researcher (22nd July - 06th August 2015) in collaboration with Prof. Jan Reedijk and Prof. E. Bouwman at Metals and Catalysis, Biomimetics & Inorganic Materials (MCBIM), Leiden Institute of Chemistry, Gorlaeus Laboratories, University of Leiden, THE NETHERLANDS.

 

  • Worked as Visiting Researcher (1st July-21st August, 2013) in collaboration with Prof. Jan Reedijk and Prof. E. Bouwman at Metals and Catalysis, Biomimetics & Inorganic Materials (MCBIM), Leiden Institute of Chemistry, Gorlaeus Laboratories, University of Leiden, THE NETHERLANDS.

 

  • Worked as Young Researcher (1st April, 2009-31st March, 2010) on “Organometallic Synthesis of Biological Importance” under the collaboration of Prof. Claudio Pettinari and Prof. Fabio Marchetti, Department of Chemical Sciences, University of Camerino, ITALY.

 

  • Worked as Project Fellow (June, 2007- March 2009) on project entitled “Design Of Novel Anticancer Drugs And Analysis Of Their Therapeutic Potential By In Vitro And In Vivo Studies” sponsored by Department of Biotechnology, Ministry of Science and Technology, Government of India, in Department of Chemistry, Aligarh Muslim University in collaboration with Advanced Centre for Training and Education in Cancer, Mumbai, INDIA.

AWARD AND HONOR

 

  • Ongoing Awarded as Co-Principal Investigator (Co-PI) in the ongoing Major Research project of approx. 1.2 Million Saudi Riyal (SAR) funded by King Abdullah City of Science and Technology (KACST), (2015-17)
  • Ongoing Awarded as Co-Principal Investigator (Co-PI) in the ongoing Major Research project of approx. 1.5 Million Saudi Riyal (SAR) funded by National Project of Science and Technology (NPST), (2015-17)
  • Visiting Researcher, Institute of Chemistry, University of Leiden, The Netherland (2015)
  • Research Fellow on Project title "Design, synthesis, characterization, spectroscopic and biological properties of coordination compounds of transition metals and noble metals, held together by hydrogen bonding and or ligand bridging" funded by Distinguished Scientist Fellowship Program (DSFP) as under the guidance of Dr. Jan Reedijk (Emeritus Professor), Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands (2014-2015).
  • Research Fellow on Project title "Synthesis studies of coordination and organometallic compounds for new biologically-active, magnetic or luminescent materials" funded by Distinguished Scientist Fellowship Program (DSFP) as under the guidance of Dr. Jan Reedijk (Emeritus Professor), Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands (2013).
  • Visiting Researcher, Institute of Chemistry, University of Leiden, The Netherland (2013)
  • Scholarship for Ph.D. from University Grant Commission, Government of India (2010-11).
  • Awarded Young Researcher Fellowship from the University of Camerino, ITALY (2009-10).
  • Awarded Project Fellow in Major Research Project of Rs 53.45 Lacs funded by Department of Biotechnology, Ministry of Science and Technology, Government of India (2007-09).
  • Qualified Graduate Aptitude Test held at all India level (GATE-2006).

 
RESEARCH SKILLS

  1. Hands on Synthetic Chemistry:Azoles, carbohydrate, amino acids derived organic ligands with biological significance, their coordination compounds using various metal ions viz, CuII, CoII, ZnII, SnIV, CuI, AgI, RuIII, PtII and Organometallic compounds of Ruthenium using various arenes.
  2. Experience for the characterization of synthesized compounds: Using various spectroscopic techniques viz, Uv-Vis, FTIR, (1H, 13C, 31P, 119Sn, 195Pt) NMR, EPR (solid and liquid), FAB-MS, ESI-MS, Single X-ray Crystallography.
  3. Well-Acquainted with Biophysical Techniques for the Identification of biologically active compounds: DNA and Protein binding studies using Absorption Spectroscopy, Fluorescence Spectroscopy (viz, Ethidium Bromide Quenching Assay, Phosphate Binding Assay, Tryptophan Quenching Assay, Synchronous Fluorescence), Circular Dichroism, Gel Electrophoresis, Gel Documentation.

 
INSTRUMENT HANDLED

•        Spectroscopy      

  1. Electron Paramagnetic Resonance (EPR) Spectroscopy
  2. Fluorescence spectrophotometer
  3. Cyclic voltammetry
  4. FT-IR instrument
  5. Uv-visible spectrophotometer
  6. Viscosity measurements
  7. TGA/DSC Instrument

•        Chromatography

  1. High-Performance Liquid Chromatography (HPLC)
  2. High-Performance Thin-Layer Chromatography (HP-TLC)
  3. Thin Layer Chromatography (TLC)

•        Biophysical Techniques

  • Gel Electrophoresis of Protein and DNA
  • Gel Documentation

 
COMPUTER SKILLS                  

                                                 
 
Working knowledge of Windows, MS Office, ChemDraw, Corel Draw, Photoshop, Origin, Sigma plot.
 
 
 LIST OF PUBLICATIONS
 

  1. Mohammad Usman,± Rais Ahmad Khan,± Mohd. Rashid Khan, M. Abul Farah, Jilani. P. Shaik, Narasimha R. Parine, M. Abu Khanjer, Ali Alsalme, and S. Tabassum. ‘Novel biocompatible formate bridged 1D-Cu(II) coordination polymer induces apoptosis selectively on human lung adenocarcinoma (A549) cells. Dalton transaction (Accepted) (2021).  (Impact Factor = 4.174)
  2. F. A. Qais, Iqbal Ahmad, Rais Ahmad Khan, Syed Ali Shahzad, Fohad Mabood Husain* Glyburide inhibits non-enzymatic glycation of HSA: An approach for the management of AGEs associated diabetic complications, International Journal of Biological Macromolecules 169, 143-152 (2021).  (Impact Factor = 5.162)
  3. Robina Kouser, Siffeen Zehra, Rais Ahmad Khan, Ali Alsalme, Farukh Arjmand, Sartaj Tabassum, ‘Turn‒on benzophenone‒based fluorescence and colorimetric sensor for the selective detection of Fe2+ in aqueous media: Validation of sensing mechanism by computational studies’. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 247, 119156 (2021) (Impact Factor = 3.23)
  4. Mohammad Usman, Fohad Mabood Husain, Rais Ahmad Khan, Wala Alharbi, Ali Alsalme, Hamad Al-Lohedan, and Sartaj Tabassum. ‘Organometallic Ruthenium (ƞ6-p-cymene) complexes interfering with quorum sensing and biofilm formation: An anti-infective approach to combat Multidrug-Resistance in bacteria’. New Journal of Chemistry (Accepted). (2021).  (Impact Factor = 3.288)
  5. Fohad Mabood Husain, Imran Hasan, Faizan Abul Qais, Rais Ahmad Khan, Ali Alsalme* Fabrication of Zinc oxide-Xanthan gum nanocomposite via green route: Attenuation of quorum sensing regulated virulence functions and mitigation of biofilm in Gram-negative bacterial pathogens. Coatings 10, 1190 (2020). (Impact Factor = 2.436)
  6. Imran Hasan, Charu Shekhar, Ibtisam I. BinSharfan, Ali Alsalme, Rais Ahmad Khan.* Ecofriendly Green Synthesis of ZnO Doped CuO@Alg Bionanocomposite for an Efficient Oxidative Degradation of p-Nitrophenol. ACS Omega 5, 49, 32011–32022 (2020).  (Impact Factor = 2.87)
  7. Imran Hasan, Charu Shekhar, Walaa Alharbi, M. Abu Khanjer, Ali Alsalme, Rais Ahmad Khan*. A Highly Efficient Ag Nanoparticle Immobilized Alginate-g-Polyacrylamide hybrid photocatalyst for degradation of Phenolic Compound Polymers 12, 3049 (2020).  (Impact Factor = 3.426)
  8. Imran Hasan, Ibtisam I. BinSharfan, Rais Ahmad Khan, Ali Alsalme* L-Ascorbic acid-g-Polyaniline Mesoporous Silica Nanocomposite for Efficient Removal of Crystal Violet: A Batch and Fixed Bed Breakthrough Studies Nanomaterials 10, 2402 (2020).  (Impact Factor = 4.031)
  9. Imran Hasan, Akshara Bassi, Khadijah H. Alharbi, Ibtisam I. BinSharfan, Rais Ahmad Khan, Ali Alsalme* Sonophotocatalytic Degradation of Malachite Green by Nanocrystalline Chitosan-Ascorbic Acid@NiFe2O4 Spinel Ferrite. Coatings 10, 1190 (2020).  (Impact Factor = 2.436)
  10. Hilal Ahmad, Ibtisam I. BinSharfan, Rais Ahmad Khan, Ali Alsalme* 3D Nano-architect of polyaniline-MoS2 hybrid material for Hg(II) adsorption properties” Polymers 12, 2731, (2020).  (Impact Factor = 3.426)
  11. Aurel Tăbăcaru, Rais Ahmad Khan, Giulio Lupidi, Claudio Pettinari, Synthesis, characterization and assessment of the antioxidant activity of new metal complexes derived from scorpionate ligands Molecules 25, 5298, (2020). (Impact Factor = 3.267)
  12. Hilal Ahmad, Ibtisam I. BinSharfan, Rais Ahmad Khan, Ali Alsalme*. “Effective Enrichment and Quantitative Determination of Trace Hg2+ Ions Using CdS-Decorated Cellulose Nanofibrils” Nanomaterials, 10 (11), 2218 (2020). (Impact Factor = 4.324)
  13. Riyazuddin, Samrin Bano, Rais Ahmad Khan, Ali Alsalme,* Fohad Mabood Husain, Jamal Akhter Siddique, Influence of Antimony Oxide on Epoxy Based Intumescent Flame Retardation Coating System Polymers 12, 2721 (2020).  (Impact Factor = 3.426)
  14. Hilal Ahmad, Walaa Alharbi, Ibtisam I. BinSharfan, Rais Ahmad Khan, Ali Alsalme* ‘Aminophosphonic acid Functionalized Cellulose Nanofibers for efficient extraction of Trace metal Ions’ Polymers 12 (10), 2370 (2020).  (Impact Factor = 3.426)
  15. R. Ahmed, A. Ali, M. Ahmad, Ali Alsalme, Rais Ahmad Khan, * and Farman Ali. “Phenanthroimidazole derivatives as Chemosensor for Picric Acid: A First Realistic Approach, New Journal of Chemistry 44, 20092-20100 (2020). (Impact Factor = 3.288)
  16. I. Hasan, S. Walia, K.H. Alharbi, M. AbuKhanjer, A. Alsalme, Rais Ahmad Khan* “Multi-walled Carbon Nanotube Coupled β-Cyclodextrin/PANI Hybrid Photocatalyst for Advance Oxidative Degradation of Crystal Violet”. Journal of Molecular Liquids, 317, 114216 (2020). (Impact Factor = 5.04)
  17. F. A. Qais, A. Shafiq, F. M. Husain, Rais Ahmad Khan, I. Hassan, Deciphering the interaction of plumbagin with human serum albumin: A combined biophysical and molecular modelling study, Journal of King Saud University-Science 32 (6), 2854-2862 (2020). (Impact Factor = 3.819)
  18. Rais Ahmad Khan,‡* M. Rashid Khan, M. Usman, F. Sayeed, H.A. Alghamdi, S. Alrumman, W. Alharbi, Nida N. Farshori, M.M. Al-Oqail, M.R. Siddiqui, M. Abu Khanjer, Ali Alsalme. ‘β-Carboline Copper Complex as Potential Mitochondrial Targeted Anticancer Chemotherapeutic Agent: Favorably Attenuating Human Breast Cancer MCF7 Cells via Apoptosis’ Saudi Journal of Biological Sciences, 27, 2164-2173 (2020).  (Impact Factor = 2.820)
  19. Shahanavaj Khan, S. Zaidi, A. S. Alouffi, A. Imran, Rais Ahmad Khan, I. Hassan. ‘Escherichia coli Protein Targeting in Host Cell Organelles: An In Silico Proteome-wide Study with Implications Regarding the Growth and Development of Colon Cancer’. ACS Omega 5; 7254-7261 (2020). (Impact Factor = 2.584)
  20. F.A. Qais, F.M. Husain, Rais Ahmad Khan, I. Hassan, I. Ahmad, Phytosynthesis of silver nanoparticles using Carum copticum fruit extract: Assessment of its quorum sensing and biofilm inhibitory potential against nosocomial pathogens, Microbial Pathogenesis 144; 104172 (2020). (Impact Factor = 2.581)
  21. M. Usman, Rais Ahmad Khan,*Ali Alsalme, W. Alharbi, K. H. Alharbi and S. Tabassum. ‘Structural, Spectroscopic and Chemical Bonding Analysis of Zn(II) complex,[Zn(sal)](H2O): Combined Experimental and Theoretical Investigation’ Crystals  10; 259 (2020) (Impact Factor =2.06)
  22. Imran Hasan, Rais Ahmad Khan,* W. Alharbi, K. H. Alharbi, M.  Abu Khanjer, Ali Alslame ‘Synthesis, Characterization and Photo-catalytic activity of Guar-Gum-g-Aliginate@Silver Bionanocomposite Material’ RSC Advances 10(13); 7898-7911 (2020). (Impact Factor = 3.049)
  23. M. Usman, Rais Ahmad Khan,* M. H. Jaafar, Ali Alsalme, S. Tabassum, “Co-Crystal Structure of Imidazolium-N-phthalolylglycinate Salt Hydrate: Combined Experimental and Quantum Chemical Calculations Studies.” Crystals, 10(2); 91 (2020). (Impact Factor = 2.06)
  24. Mohd Ishtikhar, Zeba Siddiqui, Fohad M Husain, Rais Ahmad Khan, Iftekhar Hassan. ‘Comparative refolding of guanidinium hydrochloride denatured bovine serum albumin assisted by cationic and anionic surfactants via artificial chaperone protocol: Biophysical insight’, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 225; 117510 (2020).  (Impact Factor = 3.23)
  25. M. F. AlAjmi, M. T. Rehman, Rais Ahmad Khan, M. A Khan, G. Muteeb, M. S. Khan, A. Alsalme, A. Hussain. ‘Understanding the interaction between α-1-acid glycoprotein (AGP) and a potential Cu/Zn metallo-drug of benzimidazole derived organic motifs: A multi-spectroscopic and molecular docking study’. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 225; 117457 (2020). (Impact Factor = 3.23)
  26. I. Hasan, Rais Ahmad Khan,* W. Alharbi, K. H. Alharbi, Ali Alslame, ‘In Situ Copolymerized Polyacrylamide Cellulose Supported Fe3O4 Magnetic Nanocomposites for Adsorptive Removal of Pb(II): Artificial Neural Network Modeling and Experimental Studies’. Nanomaterials 9(12); 1687 (2019). (Impact Factor = 4.031)
  27. P. Babji , T. N. Rao, Riyazuddin, N. Ahmad, Rais Ahmad Khan,* I. Hassan, S. A. Shahzad, F. M. Husain, Green synthesis and structural classification of Acacia nilotica mediated-silver doped titanium oxide (Ag/TiO2) spherical nanoparticles: Assessment of its antimicrobial and anticancer activity, Saudi Journal of Biological Sciences, 26; 1385-1391 (2019).  (Impact Factor = 2.820)
  28. Siffeen Zehra, Rais Ahmad Khan, Ali Alsalme, Sartaj Tabassum. “Coumarin derived "turn on" fluorescent sensor for selective detection of Cadmium (II) ion: Spectroscopic studies and validation of sensing mechanism by DFT calculations, Journal of Fluorescence, 29; 1029–1037 (2019). (Impact Factor = 1.913)
  29. F. A. Qais, A. Shafiq, H. M. Khan, F. M. Husain, Rais Ahmad Khan, Bader Alenazi, Ali Alsalme, Iqbal Ahmad "Antibacterial effect of silver nanoparticles synthesized using Murraya koenigii (L.) against multi-drug resistant pathogens" Bioinorganic Chemistry and its Applications, 2019; 4649506, 11, (2019) (Impact Factor = 2.583)
  30. Imran Hasan, F. A. Qais, F. M. Husain,* Rais Ahmad Khan,* Ali Alsalme, B. Alenazi, M.H. Jaafar, M. Usman, I. Ahmad. “Green Synthesis of dextrin based Poly (methyl methacrylate) grafted Silver nanocomposites and their antibacterial efficacy against multi-drug resistance pathogens” Journal of Cleaner Production 230; 1148-1155 (2019). (Impact Factor = 6.395).
  31. Afzal Hussain, M. F. AlAjmi, M. T. Rehman, S. Amir, F. M. Husain, A. Alsalme, M. A. Siddiqui, A. A. Al-Khedhairy, Rais Ahmad Khan.* “Copper(II) complexes as potential anticancer and NSAIDs agents: in vitro and in vivo studies” Scientific Report, 9; 5237 (2019).(Impact Factor = 4.011)
  32. Iftekhar Hassan, F. M. Husain, Rais Ahmad Khan, H. Ebaid, J. Al-Tamimi, I. M. M. Alhazza, S. Aman, K. E. Ibrahim. “Chemoprotective effect of Zinc oxide nanoparticles against potassium bromate mediated toxicity in Swiss albino rats” Environmental Science and Pollution Research, 26(10); 9966–9980 (2019). (Impact Factor = 2.914)
  33. A. Hussain, M. F. AlAjmi, M.A. Khan, A. Pervez, F. Ahmed, S. Amir, F. M. Husain, M. S. Khan, G. K. Shaik, I. Hassan, Rais Ahmad Khan and M. T. Rehman “Biosynthesized Silver Nanoparticle (AgNP) from Pandanus odorifer leaf extract exhibits Anti-Metastasis and Anti-Biofilm Potentials” Frontiers in Microbiology, 10; 8 (2019). (Impact Factor = 4.259)
  34. Rais Ahmad Khan, Sartaj Tabassum, M. Abul Farah, Mohd. Saijd Ali, Ali Alsalme, Hamad Al-Lohedan, K. M. Al-Anazi “Organometallic (ɳ6-p-cymene)Ruthenium diclofenac complex and it's Biological Studies” Journal of Biomolecular Structure and Dynamics, 37(15); 3905-3913 (2019). (Impact Factor = 3.310)
  35. N. A. Al-Shabib, F. M. Husain, F. Ahmed, Rais Ahmad Khan, M. S. Khan, F. A. Ansari, M. Z. Alam, M. A. Ahmed, M.S. Khan, M. H. Baig,  J. M. Khan, S. A. Shahzad, M. Arshad, A. Alyousef, I. Ahmad, “Low temperature synthesis of superparamagnetic iron oxide (Fe3O4) nanoparticles and their ROS mediated inhibition of biofilm formed by food-associated bacteria” Frontiers in Microbiology, 9; 2567 (2018). (Impact Factor = 4.259)
  36. N. A. Al-Shabib, F. M. Husain, Rais Ahmad Khan, M. S. Khan, M. Z. Alam, F. A. Ansari, S. Laeeq, M. Zubair, S. A. Shahzad, J. M. Khan, A. Alsalme, I. Ahmad, “Interference of Phosphane Copper(I) complexes of β-carboline with quorum sensing regulated virulence factors and biofilm in foodborne pathogenic bacteria: A First Report.” Saudi Journal of Biological Sciences, 26(2); 308-316 (2019). (Impact Factor = 2.820)
  37. S. A. Bhat, W. F. Bhat, H. Arif, M. Afsar, A. Sohail, Md. Shahnawaz Khan, Md. T. Rehman, Rais Ahmad Khan, Bilqees Bano, “Glycation induced conformational transitions in cystatin proceed to form biotoxic aggregates: A multidimensional analysis” Biochimica et Biophysica Acta (BBA) Proteins and Proteomics, 1866; 9, 989-1000, (2018). (Impact Factor = 2.609)
  38. A. Alsalme, A. A. Alsharif, H. Al-Enizi, M. Khan, S. G. Alshammari, M. A. Alotaibi, Rais Ahmad Khan, and M.R.H. Siddiqui, ‘Probing the Catalytic Efficiency of Supported Heteropoly Acids for Esterification: Effect of Weak Catalyst Support Interactions’. Journal of Chemistry, Article ID 7037461, 10 pages, (2018). (Impact Factor = 1.727)
  39. Afzal Hussain, M. F. AlAjmi, Md. Tabish Rehman, Azmat Ali Khan, Perwez Alam, Rais Ahmad Khan*. ‘Evaluation of Transition Metal complexes of Benzimidazole based Scaffold as a Promising Anticancer Chemotherapeutics’. Molecules, 23(5); 1232, 18 pages (2018). (Impact Factor = 3.060)
  40. M. F. AlAjmi, Afzal Hussain, Md. Tabish Rehman, Azmat A. Khan, Perwez A. Sheikh, and Rais Ahmad Khan.* “Design, Synthesis, and Biological Evaluation of Benzimidazole-Derived Biocompatible Copper(II) and Zinc(II) Complexes as Anticancer Chemotherapeutics” International Journal of Molecular Sciences, 19(5); 1492, 22 pages (2018). (Impact Factor = 4.183)
  41. M. Usman, S.Tabassum, F. Arjmand, Rais Ahmad Khan, M. S. Ali, H.  A. AlLohedan, Ali Alsalme, M. A. Farah, K. M. Al-Anazi and M. Musheer. “CuII-NaI heteronuclear complex as anticancer entity against human breast cancer cell lines: DNA binding, cleavage, and Computational studies”. Inorganica Chimica Acta, 479; 229–239 (2018). (Impact Factor = 2.433)
  42. Ali Alsalme, Rais Ahmad Khan,* Arwa M. Alkathiri,  M. Sajid Ali, M. Jaafar, Sartaj Tabassum, H. Al-Lohedan, “Biophysical Investigation on the Binding of Silver Norharmane Compounds to Human Serum Albumin; Insights from Multi-spectroscopic Techniques and Molecular Docking Studies” Bioinorganic Chemistry and its Applications, 2018, pages 11, (2018) (Impact Factor = 2.583).
  43. Mohammad Usman, Farukh Arjmand, Rais Ahmad Khan, Ali Alsalme, Musheer Ahmad, Mousumi S. Bishwas and Sartaj Tabassum “Tetranuclear Cubane Cu4O4 complexes as prospective Anticancer Agents: Design, Synthesis, Structural Elucidation, Magnetism, Computational Studies and Cytotoxicity Assays” Inorganica Chimica Acta, 473; 121-132 (2018) (Impact Factor = 2.433)
  44. N. Al-Shabib, Fahad M. Hussain, I. Hassan, M. Khan, F. Ahmed, F. Qais, M. Oves, M. Rahman, Rais Ahmad Khan, Altaf Khan, I. M Alhazza, S. Aman, S. Noor, H. Ebaid, J. Al-Tamimi, J. M. Khan, A. Al-Ghadeer, K. A. Khan, I. Ahmad and A.Hussain, “Bio-fabrication of non-toxic Zinc oxide nanoparticle from Ochradenus baccatus leaves: Broad-spectrum anti-biofilm activity and protein binding studies” Journal of Nanomaterials, Article ID 8612158, 14 pages (2018). (Impact Factor = 2.233)
  45. N. Rabbani, S. Tabrez, B. Islam, M. T. Rehman, A. M. Alsenaidy, M. F. AlAjmi, Rais Ahmad Khan, M. A. Alsenaidy, M. S. Khan. “Characterization of colchicine binding with normal and glycated albumin: In-vitro and molecular docking analysis” Journal of Biomolecular Structure and Dynamics, 36; 3453-3462 (2018). (Impact Factor = 3.310)
  46. W. Natongchai, Rais Ahmad Khan, A. Alsalme, R. R. Shaikh. “YCl3-catalyzed Highly Selective Ring Opening of Epoxides by Amines at Room Temperature and under Solvent-free Conditions, Catalysts, 7, 340 (2017). (Impact Factor = 3.444)
  47. Mohammad Usman, Farukh Arjmand, Rais Ahmad Khan, Ali Alsalme, Musheer Ahmad and Sartaj Tabassum. “Biological evaluation of dinuclear copper complex/dichloroacetic acid cocrystal against human breast cancer: design, synthesis, characterization, DFT studies and cytotoxicity assays, RSC Advances, 7; 47920–47932 (2017). (Impact Factor = 3.049)
  48. Hanan M. Al-Yousef, Nasser A. Al-Shabib, S. Laeeq, Rais Ahmad Khan,* Ali Alsalme, M. F. Al Ajmi, Md. Tabish Rehman, Fohad M. Husain. “Onion Peel Ethylacetate Fraction and Its Derived Constituent Quercetin 4`-O-β-D Glucopyranoside Attenuates Quorum Sensing Regulated Virulence and Biofilm Formation” Frontiers in Microbiology, 8; 1675 (2017). (Impact Factor = 4.259)
  49. Mohd. Usman, M. Zaki, Rais Ahmad Khan, Ali Alsalme, M. Ahmad, and Sartaj Tabassum. “Coumarin centered copper(II) complex with appended-imidazole as cancer chemotherapeutic agents against lung cancer: molecular insight via DFT-based vibrational analysis” RSC Advances, 7; 36056–36071 (2017). (Impact Factor = 3.049)
  50. Sartaj Tabassum, Mohd. Afzal, H. Al-Lohedan, Mehvash Zaki, Rais Ahmad Khan, and M. Ahmad “Synthesis and Structure Elucidation of New Open Cubane Tetranuclear [CuII4] Clusters: Evaluation of the DNA/HSA Interaction and pBR322 DNA Cleavage Pathway” Inorganica Chimica Acta, 463; 142–155 (2017). (Impact Factor = 2.433)
  51. Nasser A. Al-Shabib, Fohad M. Husain, Iqbal Ahmad, Mohd. Shahnawaz Khan, Rais Ahmad Khan, Javed M. Khan, “Rutin inhibits mono and mixed biofilm formation by foodborne drug resistant Escherichia coli and Staphylococcus aureus” Food Control, 79; 325-332 (2017) (Impact Factor = 4.248)
  52. Rais Ahmad Khan, Mohammad Usman, Dhivya Rajakumar, Perumalsamy Balaji, Ali Alsalme, Farukh Arjmand, Khalid Al Farhan, M. A. Akbarsha, Fabio Marchetti, Claudio Pettinari, and Sartaj Tabassum. “Heteroleptic Copper(I) Complexes of “Scorpionate” Bis-pyrazolyl Carboxylate Ligand with Auxiliary phosphine as potential anticancer agents: An Insight to Cytotoxic Mode” Scientific Reports (Nature), 7; 45229 (2017) (Impact Factor = 4.011)
  53. Rais Ahmad Khan, Andreia de Almeida, Khalid Al-Farhan, Ali Alsalme, Angela Casini, Mohamed Ghazzali, and Jan Reedijk “Transition-metal norharmane compounds as possible cytotoxic agents: new insights based on a coordination chemistry perspective" Journal of Inorganic Biochemistry, 165; 128–135 (2016) (Impact Factor = 3.224)
  54. Nasser A. Al-Shabib, Fohad M. Husain, Faheem Ahmed, Rais Ahmad Khan, Iqbal Ahmad, Edreese Alsharaeh, M. S. Khan, Afzal Hussain, Md T. Rehman, M. Yusuf, I. Hassan, J.M. Khan, G. M. Ashraf, Ali Alsalme, M. F. Al-Ajmi, V. V. Tarasov & G. Aliev “Biogenic synthesis of Zinc oxide nanostructures from Nigella sativa seed: Prospective role as food packaging material inhibiting broad-spectrum quorum sensing” Scientific Report (Nature),  6; 36761 (2016) (Impact Factor = 4.011)
  55. Rais Ahmad Khan, Fabian Dielmann, F. Ekkehardt  Hahn, Khalid Al-Farhan, Ali Alsalme, Xue Liu and Jan Reedijk “Tetrahedrally coordinated luminescent copper(I) compounds containing halide, phosphane and norharmane ligands”. Polyhedron, 111; 173-178 (2016) (Impact Factor = 2.284)
  56. Ali Alsalme, Sameen Laeeq, Sourabh Dwivedi, Mohd. Shahnawaz Khan, Javed Musarrat, Khalid Al-Farhan, and Rais Ahmad Khan.* “Synthesis, characterization of α-Amino acid Schiff base derived Ru/Pt complexes: induces cytotoxicity in HepG2 cell via protein binding and ROS generation.” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 163; 1-7 (2016) (Impact Factor = 2.931).
  57. Mohamed F. Al Ajmi, Afzal Hussain, Ali Alsalme, and Rais Ahmad Khan,* “In vivo assessment of newly synthesized achiral copper(II) and zinc(II) complexes of benzimidazole derived scaffold as a potential analgesic, antipyretic and anti-inflammatory” RSC Advances, 6; 19475-19481  (2016) (Impact Factor = 3.049)
  58. Alessandra Folda, Valeria Scalcon, Mohamed Ghazzali, Mohammed H. Jaafar, Rais Ahmad Khan, Angela Casini, Anna Citta, Alberto Bindoli, Maria Pia Rigobello, Khalid Al-Farhan, Ali Alsalme and Jan Reedijk “Insights into the strong in-vitro anticancer effects for bis(triphenylphosphane)iminium compounds having perchlorate, tetrafluoridoborate and bis(chlorido)argentate anions” Journal of Inorganic Biochemistry, 153; 346–354 (2015) (Impact Factor = 3.224)
  59. Sartaj Tabassum, Ahmad Asim, Rais Ahmad Khan, Farukh Arjmand, Rajakumar Divya, Perumalsamy Balaji and Mohammad Abdulkader Akbarsha. "A multifunctional molecular entity CuII-SnIV heterobimetallic complex as potential cancer chemotherapeutic agents: DNA binding/cleavage, SOD mimetic, topoisomerase Iα inhibitory and in vitro cytotoxic activities" RSC Advances, 5; 47439–47450 (2015) (Impact Factor = 3.049)
  60. Imtiyaz Yousuf, Farukh Arjmand, Sartaj Tabassum, Loic Toupet, Rais Ahmad Khan, Maqsood A. Siddiqui, "Mechanistic insights of a novel chromone–appended Cu(II) anticancer drug entity: In vitro binding profile with DNA/RNA substrates and cytotoxic activity against MCF-7 and HepG2 cancer cells" Dalton transaction RSC, 44; 10330-10342 (2015) (Impact Factor = 4.099)
  61. Rais Ahmad Khan, Khalid Al-Farhan, Andreia de Almeida, Ali Alsalme, Angela Casini, Mohamed Ghazzali, Jan Reedijk, “Light-stable bis(norharmane)silver(I) compounds: Synthesis, characterization and antiproliferative effects in cancer cells.” Journal of Inorganic Biochemistry, 140; 1-5 (2014) (Impact Factor = 3.224)
  62. Rais Ahmad Khan, Farukh Arjmand, Sartaj Tabassum, Magda Monari, Fabio Marchetti, Claudio Pettinari, “Organometallic ruthenium(II) scorpionate as topo IIα inhibitor; in vitro binding studies with DNA, HPLC analysis and its anticancer activity.” Journal of Organometallic Chemistry, 771; 47-58 (2014) (Impact Factor = 2.066)
  63. Ali Alsalme, Mohamed Ghazzali, Rais Ahmad Khan, Khalid Al-Farhan, and Jan Reedijk. "A novel trinuclear μ3-hydroxido-bridged Cu(II) compound; a molecular cluster, stabilized by hydrogen bonding, bridging pyrazolates, terminal pyrazoles, water and nitrate anions. Polyhedron, 75; 64-67 (2014) (Impact Factor = 2.284)
  64. Rais Ahmad Khan, Shipra Yadav, Zahid Hussain, Farukh Arjmand and Sartaj Tabassum "Carbohydrate linked Organotin (IV) Complexes as Human Topoisomerase Iα inhibitor and their antiproliferative effects against human carcinoma cell line (Huh7) by transcriptional regulation of specific gene" Dalton Transaction RSC 43, 2534-2548 (2014) (Impact Factor = 4.052)
  65. Sartaj Tabassum, Ahmad Asim, Rais Ahmad Khan, Zahid Hussain, Saurabh Srivastav, Saripella Srikrishna and Farukh Arjmand. “Chiral Heterobimetallic Complexes Targeting Human DNA-Topoisomerase Iα.” Dalton Transaction, RSC 42, 16749-16761 (2013) (Impact Factor = 4.052)
  66.  Ali Alsalme, Khalid Al-Farhan, Mohamed Ghazzali, Miftahul Khair, Rais Ahmad Khan and Jan Reedijk. "Structure of bis(nitrato)tetrakis(pyrazole)cobalt(II): Fine tuning in the stabilisation of coordination entities by using intramolecular hydrogen bonding" Inorganic Chimica Acta, 407, 7-10 (2013) (Impact Factor = 2.433).
  67. Avijit Sarkar, Alok Ranjan Paital, Rais Ahmad Khan, Farukh Arjmand, Valerio Bertolasi, Corine Mathoniere, Rodolphe Clérac and Debashis Ray." Ligand Dependent Self-Assembly of Hydroxido-Bridged Dicopper Units Templated by Sodium Ion" Dalton Transaction RSC, 42; 12495-12506. (2013) (Impact Factor = 4.052)
  68.  Rais Ahmad Khan, Ahmad Asim, Rita Kakkar, Deepti Gupta, Vivek Bagchi and Sartaj Tabassum. "Crystal Structure of heterobimetallic Ruthenium (II)-Tin(IV) complex; in vitro DNA Binding Studies with CT-DNA, Topo I Inhibition activity and DFT Calculations" Organometallics ACS, 32; 2546−2551. (2013) (Impact Factor = 4.100)
  69. Ashish Kumar Srivastava, Niraj Kumari, Rais Ahmad Khan, Richa Rai, Geeta Rai, Sartaj Tabassum and Lallan Mishra. "DNA cleavage activity and cytotoxicity of mononuclear and trinuclear Cu(II) complexes containing 1H-pyrazole-3,5-dicarboxylic acid as ligand" Indian Journal of Chemistry, Sec A, CSIR-NISCAIR, 52A, 835-844. (2013) (Impact Factor = 0.483)
  70. Sartaj Tabassum, Girish C. Sharma, Ahmad Asim, Ameer Azam and Rais Ahmad Khan. "Chiral Nano Heterobimetallic DNA Receptors: in vitro binding studies, cleavage activity and DNA condensation studies (TEM and AFM imaging)" Journal of Organometallic Chemistry, 713 123-133. (2012) (Impact Factor = 2.066)
  71. Sartaj Tabassum, Mehtab Parveen, Akhtar Ali, Mahboob Alam, Anis Ahmad, Asad U Khan and Rais Ahmad Khan. "Synthesis of Novel Aryl-1,2,4,5-tetrazinane-3-thiones, in-vitro DNA Binding Studies, Nuclease Activity and its Antimicrobial activity" Journal of Molecular Structure, 1020, 33-40 (2012) (Impact Factor = 2.120)
  72. Sartaj Tabassum, Rais Ahmad Khan, Farukh Arjmand, Mubashira Aziz, Aarti S. Juvekar and Surekha M. Zingde "Glycoconjugate heterobimetallic complexes: synthesis, binding studies, nuclease activity, groove binding affinity and in-vitro cytotoxicity" Carbohydrate Research, 346, 2886–2895 (2011) (Impact Factor = 1.873)
  73. Ruchi Gaur, Rais Ahmad Khan, Sartaj Tabassum, Priyanka Shah, Mohammad I. Siddiqi and Lallan Mishra,"Interaction of a ruthenium(II)-chalcone complex with double stranded DNA: spectroscopic, molecular docking and nuclease properties" Journal of Photochemistry and Photobiology A: Chemistry, 220 145-152 (2011) (Impact Factor = 3.261)
  74. Sartaj Tabassum, Rais Ahmad Khan, Farukh Arjmand, Subrata Sen, J. Kayal, Aarti S. Juvekar and Surekha M. Zingde. "Synthesis and characterization of glycoconjugate tin(IV) complexes: In vitro DNA binding studies, cytotoxicity, and cell death" Journal of Organometallic Chemistry, 696; 1600-1608 (2011) (Impact Factor = 2.066)
  1. Sartaj Tabassum, Rais Ahmad Khan, Farukh Arjmand, Aarti S. Juvekar and Surekha M. Zingde, "Synthesis of carbohydrate-conjugate heterobimetallic CuII-Sn2IV and ZnII-Sn2IV complexes; their interactions with CT DNA and nucleotides; DNA cleavage, in-vitro cytotoxicity" European Journal of Medicinal Chemistry, 45; 4797-4806, (2010) (Impact Factor = 4.833)

 
PAPERS PRESENTED/ CONTRIBUTED in CONFERENCES/ SYMPOSIUM/ WORKSHOPS

 

  1. Presented Paper “International Chemistry Conference” held on 08-10, November 2016 at King Saud University, Riyadh, Kingdom of Saudi Arabia.
  2. Paper contributed in IUPAC-2015, August 07-14 (2015) held at BEXCO, BUSAN, KOREA.
  3. Paper contributed in 12th European Biological Inorganic Chemistry Conference (EUROBIC-12) 24 - 28 August 2014, at Zurich, SWITZERLAND.
  4. Paper contributed in 41st International Conference on Coordination Chemistry (ICCC-41) 21 - 25 July 2014, at Suntec Singapore, SINGAPORE.
  5. Presented Paper in International Conference “Global Challenges- The Role of Chemistry in Giving their Solutions-ICC” held on 11-15th, June, 2011 at Bangkok, THAILAND.
  6. Presented Paper “International Conference on Chemistry; Frontier and Challenges- ICCFC” held on 05-06, March 2011 at Aligarh Muslim University, Aligarh, INDIA.
  7. Presented Paper in National Conference CRSI-RSC “Chemical Research Society of India and Royal Society of Chemistry” held 04-06, February 2011 at NISER-KIIT, Bhubaneswar, INDIA. 
  8. Presentation Paper in National Conference “Indian Council of Chemist-ICC” held on 19-21, December 2010 at Panjab University, Chandigarh, INDIA.
  9. Paper contributed in Gordon Research Conference, June 20-25 (2010). held at University of New England, Biddeford, USA.
  10. Presented Paper in International School of Organometallic Chemistry “ISOC” 7th Edition, 05-09, September, 2009 at the University of Camerino, ITALY.
  11. Presented Paper in an International Conference on “Interplay of Chemical and   Biological Science: Impact on Health and Environment-ISCBC” held on 04th March,   2009 at Delhi University, INDIA.
  12. Participated in “SERC” Summer School in Modeling and Informatics in Drug Design From 30th June to 18th July, 2008 organized by National Institute of Pharmaceutical Education and Research, Punjab, INDIA.
  13. Participated in Course on Polymer Characterization organized by the POLYCHAR World Forum on Advanced Materials sponsored by IUPAC, held on 14th February 2008 at India Institute of Technology (IIT), Delhi, INDIA.

 
 
COUNTRY VISITED FOR RESEARCH

 

  • UNIVERSITY OF LEIDEN, NETHERLANDS (EUROPE) (2015).
  • UNIVERSITYOF LEIDEN, NETHERLANDS (EUROPE) (2013).
  • UNIVERSITY  OF CAMERINO, ITALY (EUROPE) (2009-10).

 

الجامعه
A