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أمــل بنت محمد بن عبدالعزيز المحيميد

Associate Professor

استاذ مشارك- مساعدة وكيلة كلية العلوم للدراسات العليا والبحث العلمي

كلية العلوم
مبنى 5- الدور الثالث- مكتب رقم 188
المنشورات
مقال فى مجلة
2013

Ion Selective Electrodes for Determination of Cefditoren Pivoxil in Pharmaceutical Formulations and Biological Fluids

Aly, Salma A. Al-Tamimi, Amal M. Al-Mohaimeed*, Nawal A. Alarfaj, Fatma A. . 2013

Cefditoren pivoxil; Ion-selective electrodes; Potentiometric determination; pharmaceutical formulat

 

Newly developed coated wire electrodes have been developed for determination of cefditoren pivoxil (CTP) in pure form, pharmaceutical preparations and in biological fluids. The selective electrodes were fabricated based on the incorporation of cefditoren pivoxil with the ion exchangers, phosphomolybdic acid (CTP-PMA), phosphotungstic acid (CTP-PTA) and a mixture of both (CTP-PMA/PTA). The potential responses of the electrodes were influenced by the pH of tested solution. Under the condition of pH 5-10, the electrodes exhibit linear response over concentration range 1.0 × 10-7 - 1.0 × 10-2 mol/L with Nernstian slopes (56.29 ± 0.09, 54.60 ± 0.09 and 58.17 ± 0.28 mV/ decade at 25 °C) for the three electrodes, respectively. The influence of possible interfering species such as common inorganic cations, amino acids and different pharmacological related compounds was studied. The electrodes were successfully applied to determination of the drug in tablets by direct and standard addition potentiometry. Statistical student's t-test and F-test showed insignificant systematic error between proposed and reported methods

نوع عمل المنشور
ورقة بحثية من رسالة الدكتوراه
رقم المجلد
8
رقم الانشاء
8
مجلة/صحيفة
International Journal of Electrochemical Scienece
الصفحات
3988 الى 4001
مزيد من المنشورات
publications

: A simple, rapid and highly sensitive spectrofluorimetric method was developed for determination of gemifloxacin mesylate (GFX) in tablets. The method is based on measuring the native fluorescence…

بواسطة Amal M. Al-Mohaimeed*, Salma A. Al-Tamimi, , Nawal A. Alarfaj, Fatma A. Aly
2014
publications

A simple, accurate and precise potentiometric method was developed for the determination of gemifloxacin mesylate (GFX). Three ion selective coated wire sensors have been constructed from the…

بواسطة Amal M. Al-Mohaimeed*, Salma A. Al-Tamimi, , Nawal A. Alarfaj, Fatma A. Aly
2012
publications

 

بواسطة Salma A. Al-Tamimi, Amal M. Al-Mohaimeed*, Nawal A. Alarfaj, Fatma A. Aly
2013