Chem 640 - Advanced Organic Synthesis

I. Retrosynthesis
1. Retrosynthesis Analysis
2. Functional Group Interconversions
3. Retrosynthesis of Hydrocarbon Targets
4. Example problem illustrating C-C, C=C formation. Scope of SN2 reaction using carbon nucleophiles.
5. Retrosynthesis of Monofunctional Targets

II. Oxidations
1. Metal Based Reagents
2. Non-Metal Based Reagents
3. Epoxidations

III. Reduction
1. Reduction of Carbonyl and other Functional Groups

IV. Carbon - Carbon Bond Formation

V. Sigmatropic Rearrangements