عبدالمجيد بن عبدالله العياف

Hybrids of spirooxindole and 1,2,3-triazole have been the subject of extensive research because of their potential

as multitarget anticancer pharmaceuticals. Potential novel anticancer…

A new series of spiro-heterocycles derived from pyrazole–indenoquinoxaline scaffolds 4a–n and 5a–m was designed and

synthesized via one-pot multi-component reaction-based a [3 + 2]…

Several aspects of apoptosis signaling have been explored for

managing non-small cell lung cancer (NSCLC). While inhibiting

oncogenic kinases like PIM-1 and CDK2 has shown promise…