Path 211

Credit Hours:

 10 credit hours.

Course Description:

This course is divided into general and systemic pathology. General pathology deals with the basic concepts of various diseases. Systemic pathology deals with diseases affecting specific organ systems.

Course Contents:

A. General Pathology

1. Inflammation and repair

1.1 Definition, causes and manifestation of inflammation

1.2 Local vascular response and chemotaxis

1.3 The inflammatory exudates and chemical mediators

1.4 Types and fates of acute inflammation

1.5 Types and fates of chronic inflammation

1.6 Repair and regeneration

2. Degeneration, infiltration and necrosis

2.1 Fatty, mucoid, hyaline and fibrinoid changes

2.2 Amyloidosis

2.3 Pathological calcifications and pigmentations

2.4 Glycogen and uric acid accumulations

2.5 Types of necrosis and gangrene

3. Hemodynamics

3.1 Hyperemia, venous congestion

3.2 Thrombosis, embolism, infarction

3.3 Hemorrhage and shock

4. Granulomatous inflammation

4.1 Tuberculosis

4.2 Leprosy

4.3 Sarcoidosis

4.4 Schistosomiasis

5. Disorders of growth

5.1 Atrophy, hypertrophy and hyperplasia

5.2 Metaplasia, dysplasia and carcinoma in-situ

6. Neoplasia

6.1 Definition, classification, characteristics of benign and malignant tumors

6.2 Spread of malignant tumors

6.3 Characteristics of carcinomas versus sarcomas and their mode of spread

6.4 Examples of epithelial tumors; papillomas, adenomas and carcinomas

6.5 Examples of mesenchymal tumors; muscle tumors, vascular tumors and melanocytic tumors

6.6 Hamartomas, teratomas and embryonic tumors

6.7 Carcinogenesis

6.8 Complications of benign and malignant tumors

6.9 Tumor markers

7. Immunopathology

7.1 Immune-complex diseases

7.2 Autoimmune diseases

7.3 Immunodeficiency disorders

7.4 HLA typing

B. Systemic Pathology:

1. Cardiovascular system

1.1 Ischemic heart diseases and myocardial infarction

1.2 Hypertension

1.3 Rheumatic heart diseases

1.4 Endocarditis and pericarditis

1.5 Vasculitis and aneurysms

1.6 Atherosclerosis

2. Respiratory system

2.1 Bronchiactasis and Asthma

2.2 Emphysema

2.3 Pneumonia

2.4 Pneumoconiosis and pulmonary fibrosis

2.5 Tumors of the upper respiratory tract

2.6 Tumors of the lungs

3. Alimentary system

3.1 Tumors of the oral cavity, salivary glands and esophagus

3.2 Peptic ulcer disease

3.3 Tumors of the stomach

3.4 Malabsorption diseases; Celiac disease

3.5 Malabsorption diseases; Tropical sprue

3.6 Inflammatory bowel diseases, amebic and bacillary dysenteries

3.7 Tumors of the small and large intestines

4. Hepatobiliary system

4.1 Hepatitis

4.2 Cirrhosis

4.3 Tumors of the liver

4.4 Diseases of the gallbladder

4.5 Diseases of the pancreas

5. Urinary system

5.1 Glomerulopathies

5.2 Pyelonephritis

5.3 Urinary tract obstruction and urolithiasis

5.4 Tumors of the kidney and urinary bladder

6. Genital system

6.1 Carcinoma of the cervix

6.2 Endometrial hyperplasia and carcinoma

6.3 Ovarian cysts

6.4 Ovarian tumors

6.5 Benign breast diseases

6.6 Tumor of the breast

6.7 Prostatic hyperplasia and carcinoma

6.8 Tumors of the testis

7. Lymph nodes and lymphatic tissue

7.1 Hodgkin's lymphoma

7.2 Non-Hodgkin's lymphoma

8. Central nervous system

8.1 Meningitis and encephalitis

8.2 Intracranial tumors

9. Endocrine system

9.1 Goiter and types of thyroiditis

9.2 Tumors of the thyroid

9.3 Tumors of the pituitary, adrenal and parathyroid glands

10. Bone

10.1 Osteomyelitis

10.2 Tumors of the bone

References:

Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. 9th ed. Elsevier Saunders; 2013. Philadelphia, PA.