Cadmiumis considered one of the most important heavy metals contaminant to both soil and plants that possess
a great threat to the whole ecosystem. In the presentwork, the role of Moringa oleifera leaf extractwas studied to
reduce the negative effects of cadmium chloride (CdCl2) on Lepidium sativum was examined. Results showed a
significant increase in the Malondialdehyde (MDA) and H2O2 content of Lepidium sativum with increasing concentrations
of cadmium (0, 30, 60 and 120 mgL−1) while their content decreased notably after the addition of
Moringa oleifera leaf extract. However, compared to the control plants there was an increase in non-enzymatic
antioxidant content, such as Glutathione (GSH) and Ascorbic Acid (ASA) whenever cadmium concentrations
were increased even after their treatment with Moringa oleifera leaf extract. Also, enzymatic antioxidant activity
such as (SOD, CAT, PPO, ASO and GR) were increased. This study demonstrates the effect of Moringa oleifera leaf
extract on Antioxidant System of Lepidium sativum under Cadmium Stress